Enantioselective methodologies for the synthesis of spiro compounds

被引：697

作者：

Rios, Ramon ^{[1
]}

机构：

[1] Univ Barcelona, Dept Quim Organ, E-08028 Barcelona, Spain

来源：

CHEMICAL SOCIETY REVIEWS | 2012年 / 41卷 / 03期

关键词：

ORGANOCATALYTIC CASCADE REACTIONS; ASYMMETRIC ALDOL REACTIONS; DOMINO REACTIONS; PALLADIUM(II) COMPLEXES; SPIROCYCLIC OXINDOLES; 2+2+2 CYCLOADDITION; ALLYLIC ALKYLATION; RHODIUM(I) COMPLEX; CONCISE SYNTHESIS; BETA-LACTONES;

D O I：

10.1039/c1cs15156h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The enantioselective synthesis of spirocycles has been a long time pursued dream for organic chemists. Since the first pioneering efforts of Tamao and coworkers in the enantioselective construction of spirosilanes, many efforts have been devoted to the development of new and promising asymmetric methodologies. Remarkably, with the advent of organocatalysis the number of methodologies has been highly increased. The aim of this tutorial review is to summarize the last trends and developments reported in the literature in the enantioselective synthesis of spirocompounds.

引用

页码：1060 / 1074

页数：15

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