Rare-Earth-Catalyzed C-H Bond Addition of Pyridines to Olefins

被引：214
|
作者：
Guan, Bing-Tao
Hou, Zhaomin [1 ]
机构：
[1] RIKEN Adv Sci Inst, Organometall Chem Lab, Wako, Saitama 3510198, Japan
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 133卷 / 45期
关键词：
STYRENE-STYRENE SEQUENCES; SYNDIOSPECIFIC COPOLYMERIZATION; SELECTIVE ALKENYLATION; AROMATIC HETEROCYCLES; INSERTION CHEMISTRY; ALKYNYL COMPLEXES; COUPLING REACTION; SCANDIUM; ACTIVATION; POLYMERIZATION;
D O I：
10.1021/ja208129t
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient and general protocol for the ortho-alkylation of pyridines via C-H addition to olefins has been developed, using cationic half-sandwich rare-earth catalysts, which provides an atom-economical method for the synthesis of alkylated pyridine derivatives. A wide range of pyridine and olefin substrates including alpha-olefins, styrenes, and conjugated dienes are compatible with the catalysts.
引用
收藏
页码：18086 / 18089
页数：4
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