The Relationship Between Symptom Prevalence and Severity and Cancer Primary Site in 796 Patients With Advanced Cancer

被引：26

作者：

Kirkova, Jordanka ^{[1
]}

Rybicki, Lisa ^{[2
]}

Walsh, Declan ^{[1
]}

Aktas, Aynur ^{[1
]}

Davis, Mellar P. ^{[1
]}

Karafa, Matthew T. ^{[2
]}

机构：

[1] Cleveland Clin, Taussig Canc Inst, Dept Solid Tumor Oncol, Harry R Horvitz Ctr Palliat Med & Support Oncol, Cleveland, OH 44195 USA

[2] Cleveland Clin, Lerner Res Inst, Dept Quantitat Hlth Sci, Cleveland, OH 44195 USA

来源：

AMERICAN JOURNAL OF HOSPICE & PALLIATIVE MEDICINE | 2011年 / 28卷 / 05期

关键词：

cancer; symptom; prevalence; severity; primary site; symptom assessment; COMMON SYMPTOMS; PAIN; CYTOKINES; POPULATION; DEPRESSION; DISTRESS; DISEASE; SLEEP;

D O I：

10.1177/1049909110391464

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Knowledge of differences in symptom experience between cancer sites may help better understand symptom pathophysiology. A total of 38 symptoms in 796 consecutive patients with advanced cancer were retrospectively analyzed. Symptom prevalence and severity were compared among the 12 primary site groups (PSGs) by the chi-square test. Pairwise comparisons determined which sites differed. Pain, fatigue, weakness, lack of energy, and anorexia had the highest overall prevalence but did not differ among PSGs. The 3 most common neuropsychological symptoms (insomnia, depression, and anxiety) also did not vary among PSGs. Nineteen (50%) symptoms varied significantly between PSGs, in prevalence (17), severity (14), or both (12). Nine of 17, 6 of 14, and 6 of 12 were gastrointestinal symptoms. Symptoms which varied by PSGs can be included in cancer site-specific symptom assessment instruments.

引用

页码：350 / 355

页数：6

共 33 条

[1] CANCER-RELATED PAIN .1. PREVALENCE IN AN OUTPATIENT SETTING AS A FUNCTION OF STAGE OF DISEASE AND TYPE OF CANCER [J].