Efficient access to fused ring compounds via dearomatization/ring-closing metathesis

被引：8

作者：

Kündig, EP ^{[1
]}

Bellido, A ^{[1
]}

Kaliappan, KP ^{[1
]}

Pape, AR ^{[1
]}

Radix, S ^{[1
]}

机构：

[1] Univ Geneva, Dept Organ Chem, CH-1211 Geneva 4, Switzerland

来源：

SYNLETT | 2003年 / 15期

关键词：

dearomatization; arene chromium complex; phenyl oxazoline; ring closing closing metathesis;

D O I：

10.1055/s-2003-43330

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The complex (p-methoxyphenyl oxazoline)Cr(CO)(3) is converted in two steps into a cis-fused [6,8] ring system containing a cycohexadiene ring unit, a cyclooctenone ring and a quaternary carbon at the ring junction. The key steps involve a diastereoselective addition of three C-substituents across an arene double bond, followed by an allylation and ring closing metathesis step. cis-Fused [6,7], [6,6], and [6,5] ring systems are also accessible via this methodology.

引用

页码：2407 / 2409

页数：3

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