Proton magnetic resonance spectroscopic imaging in neurodegenerative diseases

被引:0
|
作者
Schuff, N [1 ]
Vermathen, P
Maudsley, AA
Weiner, MW
机构
[1] Univ Calif San Francisco, DVA Med Ctr, Magnet Resonance Unit, San Francisco, CA 94121 USA
[2] Univ Calif San Francisco, Dept Radiol, San Francisco, CA 94121 USA
来源
CURRENT SCIENCE | 1999年 / 76卷 / 06期
关键词
D O I
暂无
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Proton magnetic resonance spectroscopic imaging (H-1 MRSI) was used to investigate changes in brain metabolites in Alzheimer's disease, epilepsy, and amyotrophic lateral sclerosis. Examples of results from several ongoing clinical studies are provided. Multislice H-1 MRSI of the human brain, without volume preselection offers considerable advantage over previously available techniques. Furthermore, MRI tissue segmentation and completely automated spectral curve fitting greatly facilitate quantitative data analysis. Future efforts will be devoted to obtain full volumetric brain coverage and data acquisition at short spin-echo times (TE < 30 ms) for the detection of metabolites.
引用
收藏
页码:800 / 807
页数:8
相关论文
共 50 条
  • [1] Proton magnetic resonance spectroscopic imaging in neurodegenerative diseases
    DVA Medical Center, Department of Radiology, University of California, San Francisco, CA 94121, United States
    Curr. Sci., 6 (800-807):
  • [2] Advanced magnetic resonance imaging of neurodegenerative diseases
    Agosta, Federica
    Galantucci, Sebastiano
    Filippi, Massimo
    NEUROLOGICAL SCIENCES, 2017, 38 (01) : 41 - 51
  • [3] Advanced magnetic resonance imaging of neurodegenerative diseases
    Federica Agosta
    Sebastiano Galantucci
    Massimo Filippi
    Neurological Sciences, 2017, 38 : 41 - 51
  • [4] Automated quantitation of proton magnetic resonance spectroscopic imaging
    Rao, SB
    He, RJ
    Mehta, M
    Narayana, PA
    PROCEEDINGS OF THE 25TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-4: A NEW BEGINNING FOR HUMAN HEALTH, 2003, 25 : 513 - 516
  • [5] Value of morphological magnetic resonance imaging in the diagnosis of neurodegenerative diseases
    Hahn, U.
    Schwarz, J.
    Gratz, S.
    Kaiser, J. W.
    Jarnig, M.
    Foerstl, H.
    DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2008, 133 (18) : S15 - S18
  • [6] Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
    Mueller, Hans-Peter
    Kassubek, Jan
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2013, (77):
  • [7] Proton magnetic resonance spectroscopic imaging in pediatric major depression
    Farchione, TR
    Moore, GJ
    Rosenberg, DR
    BIOLOGICAL PSYCHIATRY, 2002, 52 (02) : 86 - 92
  • [8] Proton magnetic resonance spectroscopic imaging in patients with cerebellar degeneration
    Tedeschi, G
    Bertolino, A
    Massaquoi, SG
    Campbell, G
    Patronas, NJ
    Bonavita, S
    Barnett, AS
    Alger, JR
    Hallett, M
    ANNALS OF NEUROLOGY, 1996, 39 (01) : 71 - 78
  • [9] Reproducibility of proton magnetic resonance spectroscopic imaging in patients with schizophrenia
    Bertolino A.
    Callicott J.H.
    Nawroz S.
    Mattay V.S.
    Duyn J.H.
    Tedeschi G.
    Frank J.A.
    Weinberger D.R.
    Neuropsychopharmacology, 1998, 18 (1) : 1 - 9
  • [10] PROTON MAGNETIC-RESONANCE SPECTROSCOPIC IMAGING IN NEONATAL STROKE
    GROENENDAAL, F
    VANDERGROND, J
    WITKAMP, TD
    DEVRIES, LS
    NEUROPEDIATRICS, 1995, 26 (05) : 243 - 248