Mortality and cardiorespiratory complications in trochanteric femoral fractures: a ten year retrospective analysis

被引:49
作者
Carow, Juliane [1 ]
Carow, John Bennet [1 ]
Coburn, Mark [2 ]
Kim, Bong-Sung [3 ]
Buecking, Benjamin [4 ]
Bliemel, Christopher [4 ]
Bollheimer, Leo Cornelius [5 ]
Werner, Cornelius Johannes [6 ]
Bach, Jan Philipp [6 ]
Knobe, Matthias [1 ]
机构
[1] RWTH Aachen Univ Hosp, Dept Orthopaed Trauma, Aachen, Germany
[2] RWTH Aachen Univ Hosp, Dept Anaesthesiol, Aachen, Germany
[3] RWTH Aachen Univ Hosp, Dept Plast Surg, Hand Surg Burn Ctr, Aachen, Germany
[4] Univ Hosp Giessen & Marburg GmbH, Dept Trauma Hand & Reconstruct Surg, Campus Marburg, Marburg, Germany
[5] RWTH Aachen Univ Hosp, Dept Geriatr Med, Aachen, Germany
[6] RWTH Aachen Univ Hosp, Sect Interdisciplinary Geriatr Med, Dept Neurol, Aachen, Germany
关键词
Hip fracture; Trochanteric fracture; Mortality; Cardio-respiratory complications; Osteoporosis grade; ASA grade; Transfusion; Extramedullary implant; Nail; Minimally invasive surgery; PERCUTANEOUS COMPRESSION PLATE; IN-HOSPITAL MORTALITY; HIP FRACTURE; INTERTROCHANTERIC FRACTURES; SLIDING HIP; FEMUR; OSTEOPOROSIS; METAANALYSIS; MANAGEMENT; SURGERY;
D O I
10.1007/s00264-017-3639-3
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Purpose Despite intense research and innovations in peri-operative management, a high mortality rate and frequent systemic complications in trochanteric femoral fractures persist. The aim of the present study was to identify predictive factors for mortality and cardio-respiratory complications after different treatment methods in a ten year period at a level I trauma centre. Methods Retrospectively, all patients above 60 years of age with trochanteric femoral fracture between January 2000 and May 2011 were analyzed at a level I trauma centre. Demographic variables, comorbidities, and data regarding the surgical procedures, including required transfusions and post-operative complications, were evaluated, and the in-hospital mortality was recorded. The grade of osteoporosis was classified radiographically using the Singh index. Results The in-hospital mortality rate was 8.2% among 437 patients (male/female ratio = 110/327, mean age = 81 years) with extramedullary open (n = 144), intramedullary (n = 166), and extramedullary minimally invasive (n = 125) procedures. Significant influential factors on in-hospital mortality were identified with binary logistic regression analysis: an age of ae<yen>90 years (P = 0.011), male sex (P = 0.003), a high American Society of Anesthesiologists (ASA) grade (3-5, P = 0.042), and a high osteoporosis grade (Singh index 3-1, P = 0.011). A total of 21.5% of the study population suffered cardio-respiratory complications post-operatively. The specific mortality was 28.7% (P < 0.001), which was influenced by a high ASA grade (3-5, P = 0.002) and a high transfusion rate (P = 0.004). Minimally invasive locked plating was associated with increased cardio-respiratory complications (P = 0.031). Conclusions This study identified high patient age, distinctive comorbidities, male sex, and high osteoporosis grade as significant risk factors for increased in-hospital mortality in the treatment of trochanteric femoral fractures. Furthermore, high ASA grade and a liberal transfusion regime led to an increased incidence of cardio-respiratory complications. Patient-specific characteristics, especially osteoporosis grade and pre-existing medical conditions, may assist in the identification of high-risk patients and allow a patient-specific geriatric co-management plan.
引用
收藏
页码:2371 / 2380
页数:10
相关论文
共 42 条
[1]  
[Anonymous], 2010, BMJ, DOI [DOI 10.1136/BMJ.C1718, 10.1136/bmj.c1718]
[2]  
Balasubramanian Akhila, 2014, J Bone Joint Surg Am, V96, pe52, DOI 10.2106/JBJS.L.01781
[3]   Risk factors for complications and in-hospital mortality following hip fractures: a study using the National Trauma Data Bank [J].
Belmont, Philip J., Jr. ;
Garcia, E'Stephan J. ;
Romano, David ;
Bader, Julia O. ;
Nelson, Kenneth J. ;
Schoenfeld, Andrew J. .
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 2014, 134 (05) :597-604
[4]   Postmenopausal Osteoporosis [J].
Black, Dennis M. ;
Rosen, Clifford J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2016, 374 (03) :254-262
[5]  
Bliemel C., 2017, Int Orthop
[6]   Effect of Osteoporosis Treatment on Mortality: A Meta-Analysis [J].
Bolland, Mark J. ;
Grey, Andrew B. ;
Gamble, Greg D. ;
Reid, Ian R. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2010, 95 (03) :1174-1181
[7]   Red blood cell transfusion for people undergoing hip fracture surgery [J].
Brunskill, Susan J. ;
Millette, Sarah L. ;
Shokoohi, Ali ;
Pulford, E. C. ;
Doree, Carolyn ;
Murphy, Michael F. ;
Stanworth, Simon .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2015, (04)
[8]   AltersTraumaZentrum DGUA® [J].
Buecking, B. ;
Hoffmann, R. ;
Riem, S. ;
Sturm, J. ;
Schmucker, U. ;
Friess, T. ;
Liener, U. ;
Hartwig, E. .
UNFALLCHIRURG, 2014, 117 (09) :842-848
[9]   Association of Blood Transfusion With Increased Mortality in Myocardial Infarction A Meta-analysis and Diversity-Adjusted Study Sequential Analysis [J].
Chatterjee, Saurav ;
Wetterslev, Jorn ;
Sharma, Abhishek ;
Lichstein, Edgar ;
Mukherjee, Debabrata .
JAMA INTERNAL MEDICINE, 2013, 173 (02) :132-139
[10]   Cause of death and factors associated with early in-hospital mortality after hip fracture [J].
Chatterton, B. D. ;
Moores, T. S. ;
Ahmad, S. ;
Cattell, A. ;
Roberts, P. J. .
BONE & JOINT JOURNAL, 2015, 97B (02) :246-251