A highly selective and fast-response fluorescent probe for visualization of enzymatic H2S production in vitro and in living cells

被引:60
作者
不详
机构
[1] State Key Laboratory of Elemento-Organic Chemistry, Department of Chemical Biology, Nankai University, Tianjin
[2] State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing
[3] Collaborative Innovation Center of Chemical Science and Engineering, Tianjin
关键词
ENDOGENOUS HYDROGEN-SULFIDE; RAPID DETECTION; REDUCTION; SYNTHASE; SPECTRA; GAS;
D O I
10.1039/c5cc03707g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An o-fluorinated-azido-capped rhodamine probe can react with H2S efficiently and selectively to give large off-on fluorescence enhancement. The probe was used to develop an assay for cystathionine b-synthase acitivity and for in situ visualization of endogenously produced H2S in living cells.
引用
收藏
页码:10463 / 10466
页数:4
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