Synthesis and Spectroscopic Studies of Phenanthroimidazole-Imine Derivatives and Evaluation of Their Antioxidant Activity

被引:11
作者
Gulle, Sibel [1 ]
Erbas, Secil Celik [2 ]
Uzel, Atac [3 ]
机构
[1] Manisa Celal Bayar Univ, Fac Arts & Sci, Dept Chem, TR-45040 Muradiye, Manisa, Turkey
[2] Manisa Celal Bayar Univ, Dept Met & Mat Engn, Fac Engn, TR-45040 Muradiye, Manisa, Turkey
[3] Ege Univ, Dept Biol, Fac Sci, TR-35100 Izmir, Turkey
关键词
Phenanthroimidazole; Antioxidant activity; DPPH; Absorption and emission spectroscopy; Fluorescence; OXIDATIVE STRESS;
D O I
10.1007/s10895-017-2184-1
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The phenanthroimidazole derivatives are used in the drug industry in large scale. In this study four new phenanthroimidazole-imine derivatives were synthesized and their spectroscopic studies as well as their antioxidant behaviors were examined. Structural analyses were made by FT-IR, H-1-NMR, C-13-NMR, LC-MS spectroscopy techniques. UV-vis absorption and emission spectroscopy techniques have been used to determine the photophysical characteristics of four newly synthesized phenanthroimidazoles. The maximum absorption and emission wavelengths, molar extinction coefficients (epsilon), singlet energy levels (Es), Stokes' shift values (Delta lambda) of phenanthroimidazole-imine derivatives are given. Additionally, the antioxidant behavior of all compounds were investigated which the ascorbic acid used as standard molecule in present study.
引用
收藏
页码:217 / 223
页数:7
相关论文
共 50 条
[41]   SYNTHESIS AND ANTIOXIDANT ACTIVITY OF NOVEL PYRIMIDINE DERIVATIVES [J].
Kumar, Hemanth ;
Revanasiddappa, B. C. .
HETEROCYCLIC LETTERS, 2020, 10 (01) :57-62
[42]   Synthesis and Antioxidant Activity of Caffeic Acid Derivatives [J].
Sidoryk, Katarzyna ;
Jaromin, Anna ;
Filipczak, Nina ;
Cmoch, Piotr ;
Cybulski, Marcin .
MOLECULES, 2018, 23 (09)
[43]   The synthesis and antioxidant activity of azole derivatives of hemin [J].
Rozhkova E.A. ;
Lysko A.I. ;
Kuleshov K.V. ;
Evstigneeva R.P. .
Russian Journal of Bioorganic Chemistry, 2000, 26 (6) :419-422
[44]   Novel Quinolone Derivatives: Synthesis and Antioxidant Activity [J].
Mutyala Veera Venkata Vara Prasad ;
Radha Hunasenahalli Raghavendra Rao ;
Vadde Veeranna ;
Venkata Suryanarayana Chennupalli ;
Byrappa Sathish .
Russian Journal of General Chemistry, 2021, 91 :2522-2526
[45]   Carbazole derivatives: Synthesis, spectroscopic characterization, antioxidant activity, molecular docking study, and the quantum chemical calculations [J].
Serdaroglu, Goncagul ;
Uludag, Nesimi ;
Ercag, Erol ;
Sugumar, Paramasivam ;
Rajkumar, Parthasarathi .
JOURNAL OF MOLECULAR LIQUIDS, 2021, 330
[46]   Synthesis and antioxidant evaluation for monocarbonyl curcuminoids and their derivatives [J].
Agel, K. N. ;
Abood, E. ;
Alsalim, T. .
REVISTA INNOVACIENCIA, 2018, 6 (02)
[47]   In Silico Docking Studies and Evaluation of Antioxidant Activity of Trolox Derivatives: An Analog of Vitamin E [J].
Rawat, Pinki ;
Verma, Saurabh Manaswita ;
Rawat, Preeti ;
Kumar, Piyush .
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2021, 31 (01) :63-70
[48]   Synthesis, molecular docking, α-glucosidase inhibition, and antioxidant activity studies of novel benzimidazole derivatives [J].
Singh, Gagandeep ;
Singh, Amanjot ;
Singh, Varinder ;
Verma, Raman K. ;
Tomar, Jyoti ;
Mall, Rajiv .
MEDICINAL CHEMISTRY RESEARCH, 2020, 29 (10) :1846-1866
[49]   Ultrasonic Assisted Synthesis of Naphthalene Substituted Schiff Base Derivatives and Their Antioxidant Activity Studies [J].
Venkatesan, K. ;
Satyanarayana, V. S. V. ;
Sivakumar, A. .
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2011, 58 (05) :583-589
[50]   Synthesis of new andrographolide derivatives and evaluation of their antidyslipidemic, LDL-oxidation and antioxidant activity [J].
Pandeti, Sukanya ;
Sonkar, Ravi ;
Shukla, Astha ;
Bhatia, Gitika ;
Tadigoppula, Narender .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 69 :439-448