Synthesis and Spectroscopic Studies of Phenanthroimidazole-Imine Derivatives and Evaluation of Their Antioxidant Activity

被引：11

作者：

Gulle, Sibel ^{[1
]}

Erbas, Secil Celik ^{[2
]}

Uzel, Atac ^{[3
]}

机构：

[1] Manisa Celal Bayar Univ, Fac Arts & Sci, Dept Chem, TR-45040 Muradiye, Manisa, Turkey

[2] Manisa Celal Bayar Univ, Dept Met & Mat Engn, Fac Engn, TR-45040 Muradiye, Manisa, Turkey

[3] Ege Univ, Dept Biol, Fac Sci, TR-35100 Izmir, Turkey

来源：

JOURNAL OF FLUORESCENCE | 2018年 / 28卷 / 01期

关键词：

Phenanthroimidazole; Antioxidant activity; DPPH; Absorption and emission spectroscopy; Fluorescence; OXIDATIVE STRESS;

D O I：

10.1007/s10895-017-2184-1

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The phenanthroimidazole derivatives are used in the drug industry in large scale. In this study four new phenanthroimidazole-imine derivatives were synthesized and their spectroscopic studies as well as their antioxidant behaviors were examined. Structural analyses were made by FT-IR, H-1-NMR, C-13-NMR, LC-MS spectroscopy techniques. UV-vis absorption and emission spectroscopy techniques have been used to determine the photophysical characteristics of four newly synthesized phenanthroimidazoles. The maximum absorption and emission wavelengths, molar extinction coefficients (epsilon), singlet energy levels (Es), Stokes' shift values (Delta lambda) of phenanthroimidazole-imine derivatives are given. Additionally, the antioxidant behavior of all compounds were investigated which the ascorbic acid used as standard molecule in present study.

引用

页码：217 / 223

页数：7

共 50 条

[31] Acetophenone benzoylhydrazones as antioxidant agents: Synthesis, in vitro evaluation and structure-activity relationship studies [J].

Emami, Saeed ;

Esmaili, Zahra ;

Dehghan, Gholamreza ;

Bahmani, Maryam ;

Hashemi, Seyedeh Mandieh ;

Mirzaei, Hassan ;

Shokrzadeh, Mohammad ;

Moradi, Seyed Ershad .

FOOD CHEMISTRY, 2018, 268 :292-299

[32] Synthesis, characterization, and bio-activity evaluation of thiourea derivatives of epinephrine as antimicrobial and antioxidant agents: molecular docking studies [J].

H. Sudhamani ;

S. K. Thaslim Basha ;

S. Adam ;

B. Vijay Bhaskar ;

C. Naga Raju .

Monatshefte für Chemie - Chemical Monthly, 2017, 148 :1525-1537

[33] Synthesis, characterization, and bio-activity evaluation of thiourea derivatives of epinephrine as antimicrobial and antioxidant agents: molecular docking studies [J].

Sudhamani, H. ;

Basha, S. K. Thaslim ;

Adam, S. ;

Bhaskar, B. Vijay ;

Raju, C. Naga .

MONATSHEFTE FUR CHEMIE, 2017, 148 (08) :1525-1537

[34] Synthesis and structure-activity relationship studies of phenolic hydroxyl derivatives based on quinoxalinone as aldose reductase inhibitors with antioxidant activity [J].

Hao, Xin ;

Han, Zhongfei ;

Li, Yang ;

Li, Chenying ;

Wang, Xing ;

Zhang, Xin ;

Yang, Qin ;

Ma, Bing ;

Zhu, Changjin .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (04) :887-892

[35] Synthesis, Characterization and Antioxidant Studies of Quinazolin Derivatives [J].

Al-Azawi, Khalida .

ORIENTAL JOURNAL OF CHEMISTRY, 2016, 32 (01) :585-590

[36] Synthesis, characterization and antioxidant activity of quercetin derivatives [J].

Sun, Lei ;

Lu, Bo ;

Liu, Yandan ;

Wang, Qian ;

Li, Gao ;

Zhao, Longxuan ;

Zhao, Chunhui .

SYNTHETIC COMMUNICATIONS, 2021, 51 (19) :2944-2953

[37] Synthesis and antioxidant activity of phenolic derivatives of α-santonin [J].

Kulyyasov A.T. ;

Seitembetov T.S. ;

Adekenov S.M. .

Chemistry of Natural Compounds, 1997, 33 (2) :185-186

[38] Novel Quinolone Derivatives: Synthesis and Antioxidant Activity [J].

Prasad, Mutyala Veera Venkata Vara ;

Rao, Radha Hunasenahalli Raghavendra ;

Veeranna, Vadde ;

Chennupalli, Venkata Suryanarayana ;

Sathish, Byrappa .

RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2021, 91 (12) :2522-2526

[39] The synthesis and antioxidant activity of azole derivatives of hemin [J].

Rozhkova, EA ;

Lysko, AI ;

Kuleshov, KV ;

Evstigneeva, RP .

BIOORGANICHESKAYA KHIMIYA, 2000, 26 (06) :466-470

[40] SYNTHESIS AND ANTIOXIDANT ACTIVITY OF TWO ISOESPINTANOL DERIVATIVES [J].

Galeano, Paula L. ;

Gil, Maritza A. ;

Gil, Jesus H. ;

Otalvaro, Leon F. ;

Saez, Jairo A. ;

Rojano, Benjamin A. .

REVISTA COLOMBIANA DE QUIMICA, 2010, 39 (02) :173-180

← 1 2 3 4 5 →