Atrial Electromechanical Interval Can Identify Patients With Paroxysmal Atrial Fibrillation and is Associated With CHADS2 Score and Peak Velocity of Left Atrial Appendage

被引：12

作者：

Chao, Tze-Fan ^{[1
,2
]}

Sung, Shih-Hsien ^{[1
,2
]}

Wang, Kang-Ling ^{[1
,2
]}

Tsao, Hsuan-Ming ^{[2
,3
]}

Lin, Yenn-Jiang ^{[1
,2
]}

Chang, Shih-Lin ^{[1
,2
]}

Lo, Li-Wei ^{[1
,2
]}

Hu, Yu-Feng ^{[1
,2
]}

Tuan, Ta-Chuan ^{[1
,2
]}

Suenari, Kazuyoshi ^{[1
,4
]}

Li, Cheng-Hung ^{[1
,2
]}

Liu, Shuen-Hsin ^{[5
]}

Wu, Tsu-Juey ^{[6
]}

Yu, Wen-Chung ^{[1
,2
]}

Chen, Shih-Ann ^{[1
,2
]}

机构：

[1] Taipei Vet Gen Hosp, Div Cardiol, Dept Med, Taipei, Taiwan

[2] Natl Yang Ming Univ, Inst Clin Med, Cardiovasc Res Ctr, Taipei 112, Taiwan

[3] Natl Yang Ming Univ Hosp, Div Cardiol, Ilan, Taiwan

[4] Hiroshima Univ, Grad Sch Biomed Sci, Dept Cardiovasc Med, Hiroshima, Japan

[5] Taipei Med Univ, Shuang Ho Hosp, Dept Med, Div Cardiol, Taipei, Taiwan

[6] Taichung Vet Gen Hosp, Dept Med, Div Cardiol, Taichung, Taiwan

来源：

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY | 2011年 / 22卷 / 12期

关键词：

atrial electromechanical interval; CHADS(2) score; left atrial appendage; paroxysmal atrial fibrillation; stroke; STROKE; ANTICOAGULATION; ABLATION; VOLUME;

D O I：

10.1111/j.1540-8167.2011.02115.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Electromechanical Interval and Paroxysmal Atrial Fibrillation. Introduction: It is difficult to discriminate patients with and without paroxysmal atrial fibrillation (PAF). The atrial electromechanical interval determined by the transthoracic echocardiogram is demonstrated to be a predictor of new onset AF. The aim of our study was to investigate whether the electromechanical interval is a useful parameter to identify patients with PAF. Methods and Results: A total of 297 patients (PAF group = 103; control group = 194) with mean age of 59.4 +/- 12.4 years were enrolled. The electromechanical interval (PA-PDI) defined as the time interval from the initiation of the P-wave deflection to the peak of the mitral inflow A wave on the pulse-wave Doppler imaging was measured for every patient. Patients with PAF had significantly longer PA-PDI intervals compared with that of patients without it (152.7 +/- 13.8 ms vs 133.4 +/- 16.8 ms). The area under ROC curve based on the PA-PDI interval to diagnose PAF was 0.803 (95% confidence interval = 0.755-0.851, P < 0.001). At the cut-off value of 142 ms, the sensitivity and specificity in identifying PAF were 77.7% and 80.1%, respectively. In the PAF group, the PA-PDI interval was closely associated with the CHADS(2) score and inversely related with the peak velocity of left atrial appendage. Conclusions: The PA-PDI interval may be a useful parameter to identify patients with PAF. Further studies are necessary to evaluate the usefulness of PA-PDI intervals in diagnosing PAF in addition to the current methods and tools. (J Cardiovasc Electrophysiol, Vol. 22, pp. 1325-1330, December 2011)

引用

页码：1325 / 1330

页数：6

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