New briaranes from the South China Sea gorgonian Junceella fragilis

被引：22

作者：

Qi, SH

Zhang, S

Wen, YM

Xiao, ZH

Li, QX

机构：

[1] Chinese Acad Sci, Guangdong Key Lab Marine Mat Med, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China

[2] Chinese Acad Sci, Hainan Key Lab Trop Marine Biol & Technol, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China

[3] Zhanjiang Ocean Univ, Zhanjiang 524088, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2005年 / 88卷 / 08期

关键词：

D O I：

10.1002/hlca.200590170

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three new briarane diterpenes, junceellonoids C - E (1 - 3), along with six known briaranes, junceellin A (4), praelolide (5), and junceellolides A-D (6 - 9), were isolated from the EtOH/CH2Cl2 extracts of the South China Sea gorgonian coral Junceella fragilis. The structures of 1 - 3 were established by extensive spectroscopic analysis, including 1D- and 2D-NMR data. Compounds I and 2 exhibited mild cytotoxicity against human galactophore carcinoma (MDA-mB-231 and MCF-7) cells at the concentration of 100 mu m.

引用

页码：2349 / 2354

页数：6

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