The interplay of YKL-40 and leptin in type 2 diabetic obese patients

被引：14

作者：

El-Mesallamy, Hala O. ^{[1
]}

Mostafa, Ahmed M. ^{[1
]}

Amin, Ashraf I. ^{[2
]}

El Demerdash, Ebtehal ^{[3
]}

机构：

[1] Ain Shams Univ, Dept Biochem, Fac Pharm, Cairo, Egypt

[2] Natl Inst Diabet & Endocrinol NIDE, Dept Lab, Cairo, Egypt

[3] Ain Shams Univ, Dept Pharmacol & Toxicol, Fac Pharm, Cairo, Egypt

来源：

DIABETES RESEARCH AND CLINICAL PRACTICE | 2011年 / 93卷 / 03期

关键词：

Low-grade inflammation; Obesity; Inflammatory marker; LOW-GRADE INFLAMMATION; INSULIN-RESISTANCE; PLASMA; BIOMARKER; GENDER; MARKER;

D O I：

10.1016/j.diabres.2011.05.040

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Recently, YKL-40 has been identified as a new inflammatory marker of type 2 diabetes mellitus (T2DM), while leptin is one of the most important adipose derived hormones. However, the relationship between them has not been elucidated. Therefore this study aimed to study their correlation in obese T2DM patients. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

引用

页码：E113 / E116

页数：4

共 16 条

[11] Plasma YKL-40 A BMI-Independent Marker of Type 2 Diabetes [J].

Nielsen, Anders R. ;

Erikstrup, Christian ;

Johansen, Julia S. ;

Fischer, Christian P. ;

Plomgaard, Peter ;

Krogh-Madsen, Rikke ;

Taudorf, Sarah ;

Lindegaard, Birgitte ;

Pedersen, Bente K. .

DIABETES, 2008, 57 (11) :3078-3082

[12] YKL-40-an emerging biomarker in cardiovascular disease and diabetes [J].

Rathcke, Camilla N. ;

Vestergaard, Henrik .

CARDIOVASCULAR DIABETOLOGY, 2009, 8

[13] YKL-40, a Marker of Inflammation and Endothelial Dysfunction, Is Elevated in Patients With Type 1 Diabetes and Increases With Levels of Albuminuria [J].

Rathcke, Camilla Noelle ;

Persson, Frederik ;

Tarnow, Lise ;

Rossing, Peter ;

Vestergaard, Henrik .

DIABETES CARE, 2009, 32 (02) :323-328

[14] YKL-40, a biomarker of inflammation, is elevated in patients with type 2 diabetes and is related to insulin resistance [J].

Rathcke, CN ;

Johansen, JS ;

Vestergaard, H .

INFLAMMATION RESEARCH, 2006, 55 (02) :53-59

[15] Effects of gender, body composition, and menopause on plasma concentrations of leptin [J].

Rosenbaum, M ;

Nicolson, M ;

Hirsch, J ;

Heymsfield, SB ;

Gallagher, D ;

Chu, F ;

Leibel, RL .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1996, 81 (09) :3424-3427

[16]

Ruhl CE, 2007, AM J CLIN NUTR, V85, P1121

← 1 2 →