Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses

被引:807
作者
Sallusto, F
Lanzavecchia, A
Mackay, CR
机构
[1] Basel Inst Immunol, CH-4005 Basel, Switzerland
[2] Millennium Biotherapeut Inc, Cambridge, MA 02139 USA
来源
IMMUNOLOGY TODAY | 1998年 / 19卷 / 12期
关键词
D O I
10.1016/S0167-5699(98)01346-2
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
T-cell priming occurs in the lymphoid tissue via T cell-dendritic cell interaction. Conversely, delayed-type hypersensitivity or allergic reactions can occur in any tissue, following interaction of T helper 1 (Th1) or Th2 cells with effector leukocytes. Here, Federica Sallusto and colleagues review the role played by chemokines and chemokine receptors in positioning T cells for the immune response.
引用
收藏
页码:568 / 574
页数:7
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