Coexistence of amplitude and frequency modulations in intracellular calcium dynamics

被引：61

作者：

De Pitta, Maurizio ^{[1
,2
]}

Volman, Vladislav ^{[3
,4
]}

Levine, Herbert ^{[3
]}

Pioggia, Giovanni ^{[2
]}

De Rossi, Danilo ^{[2
]}

Ben-Jacob, Eshel ^{[1
,3
]}

机构：

[1] Tel Aviv Univ, Sch Phys & Astron, IL-69978 Tel Aviv, Israel

[2] Univ Pisa, Interdept Res Ctr E Piaggio, I-56125 Pisa, Italy

[3] Univ Calif San Diego, Ctr Theoret Biol Phys, La Jolla, CA 92093 USA

[4] Salk Inst Biol Studies, Computat Neurobiol Lab, La Jolla, CA 92037 USA

来源：

PHYSICAL REVIEW E | 2008年 / 77卷 / 03期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1103/PhysRevE.77.030903

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

The complex dynamics of intracellular calcium regulates cellular responses to information encoded in extracellular signals. Here we study the encoding of these external signals in the context of the Li-Rinzel model. We show that by control of biophysical parameters the information can be encoded in amplitude modulation (AM), frequency modulation (FM), or mixed (AM and FM) modulation. We briefly discuss the possible implications of this role of information encoding for astrocytes.

引用

页数：4

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