Evaluation of platelet parameters in healthy apheresis donors using the ADVIA 120™

被引:19
作者
Ifran, A [1 ]
Hasimi, A
Kaptan, K
Nevruz, O
Beyan, C
Erbil, K
机构
[1] Gulhane Mil Med Acad, Dept Haematol, TR-06010 Etlik, Turkey
[2] Gulhane Mil Med Acad, Dept Biochem, TR-06010 Etlik, Turkey
关键词
D O I
10.1016/j.transci.2005.04.007
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Platelet apheresis is accepted as a safe procedure and no clinically important change is observed after apheresis. The ADVIA 120 (TM) provides both an accurate platelet count and parameters describing platelet morphology and function. We studied the changes in platelet parameters of 35 healthy apheresis donors using the ADVIA 120. The mean platelet component value did not change after apheresis but the value of the platelet count was low and this reduction could be due to activation of platelets. We conclude that no remarkable changes were noted except the reduction in platelet numbers and plateletcrit which were expected to return to normal values in a few days. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:87 / 90
页数:4
相关论文
共 9 条
[1]  
DORFMAN DM, 1997, 1 INT BAYER DIAGN CE, pCH29
[2]   Platelet count and parameters determined by the Bayer ADVIA™ 120 in reference subjects and patients [J].
Giacomini, A ;
Legovini, P ;
Gessoni, G ;
Antico, F ;
Valverde, S ;
Salvadego, MM ;
Manoni, F .
CLINICAL AND LABORATORY HAEMATOLOGY, 2001, 23 (03) :181-186
[3]   Improved platelet counting using two-dimensional laser light scatter [J].
Kunicka, JE ;
Fischer, G ;
Murphy, J ;
Zelmanovic, D .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2000, 114 (02) :283-289
[4]   Sustained decreases in platelet count associated with multiple, regular plateletpheresis donations [J].
Lazarus, EF ;
Browning, J ;
Norman, J ;
Oblitas, J ;
Leitman, SF .
TRANSFUSION, 2001, 41 (06) :756-761
[5]   Evaluation of platelet parameters on the ADVIA 120 as the quality indicator for stored platelets [J].
Lim, YA ;
Hyun, BH .
CLINICAL AND LABORATORY HAEMATOLOGY, 2002, 24 (06) :377-384
[6]  
Macey MG, 1999, CYTOMETRY, V38, P250, DOI 10.1002/(SICI)1097-0320(19991015)38:5<250::AID-CYTO8>3.0.CO
[7]  
2-K
[8]   Platelet indices as quality markers of platelet concentrates during storage [J].
Singh, H ;
Chaudhary, R ;
Ray, V .
CLINICAL AND LABORATORY HAEMATOLOGY, 2003, 25 (05) :307-310
[9]  
THOMPSON CB, 1983, BLOOD, V62, P487