The Toronto IBD Global Endoscopic Reporting [TIGER] Score: A Single, Easy to Use Endoscopic Score for Both Crohn's Disease and Ulcerative Colitis Patients

被引：16
作者：
Zittan, E. [1 ,2 ,3 ,4 ]
Steinhart, A. H. [2 ]
Aran, H. [1 ]
Milgrom, R. [2 ]
Gralnek, I. M. [1 ,3 ]
Zelber-Sagi, S. [4 ]
Silverberg, M. S. [2 ]
机构：
[1] Emek Med Ctr, Dept Gastroenterol & Liver Dis, Abraham & Sonia Rochlin IBD Unit, Afula, Israel
[2] Univ Toronto, Mt Sinai Hosp, Zane Cohen Ctr Digest Dis, Dept Med, Toronto, ON, Canada
[3] Technion Israel Inst Technol, Rappaport Fac Med, Haifa, Israel
[4] Univ Haifa, Fac Social Welf & Hlth Sci, Sch Publ Hlth, Haifa, Israel
来源：
JOURNAL OF CROHNS & COLITIS | 2022年 / 16卷 / 04期
关键词：
Inflammatory bowel diseases [IBD; Crohn's disease [CD; ulcerative colitis [UC; INFLAMMATORY-BOWEL-DISEASE; INTEROBSERVER AGREEMENT; INDEX; VALIDATION; SEVERITY; CALPROTECTIN; SYSTEMS; BURDEN; DISK; TOOL;
D O I：
10.1093/ecco-jcc/jjab122
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Background and Aims We constructed the Toronto IBD Global Endoscopic Reporting [TIGER] score for inflammatory bowel disease [IBD]. The aim of our study was to develop and validate the TIGER score against faecal calprotectin [FC], C-reactive protein [CRP], and IBD Disk. Methods A cross-sectional study was performed among 113 adult patients (60 Crohn's disease [CD] and 53 ulcerative colitis [UC]). In the development and usability phase, blinded IBD experts reviewed and graded ileocolonoscopy videos. In the validity phase the TIGER score was compared with: [1] the Simple endoscopic Score for CD [SES-CD] and the Mayo endoscopic score in CD and UC, respectively; [2] FC and CRP; and [3] IBD Disk. Results Inter-observer reliability of the TIGER score per segment between reviewers was excellent: interclass correlation coefficient [ICC] = 0.94 [95% CI: 0.92-0.96]. For CD patients, overall agreement per segment between SES-CD and TIGER was 91% [95% CI: 84-95] with kappa coefficient 0.77 [95% CI: 0.63-0.91]. There was a significant correlation between TIGER and CRP [p <0.0083], and TIGER and FC [p <0.0001]. In addition, there was significant correlation between TIGER and IBD Disk [p <0.0001]. For UC patients, overall agreement per segment between Mayo endoscopic score and TIGER was 84% [95% CI: 74%-90%] and kappa coefficient 0.60 [95% CI: 0.42-0.808]. There was a significant correlation between TIGER and FC [p p Conclusions The TIGER score is a reliable and simple novel endoscopic score that can be used for both CD and UC patients and captures full endoscopic disease burden.
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页码：544 / 553
页数：10
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