Are all phytochemicals useful in the preventing of DNA damage?

被引：15
作者：
Bacanli, Merve [1 ]
Aydin, Sevtap [1 ]
Basaran, A. Ahmet [2 ]
Basaran, Nursen [1 ]
机构：
[1] Hacettepe Univ, Fac Pharm, Dept Pharmaceut Toxicol, TR-06100 Ankara, Turkey
[2] Hacettepe Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey
来源：
FOOD AND CHEMICAL TOXICOLOGY | 2017年 / 109卷
关键词：
DNA damage; Phytochemicals; INDUCED OXIDATIVE STRESS; URSOLIC ACID; HUMAN-LYMPHOCYTES; ESSENTIAL OILS; D-LIMONENE; IN-VITRO; LIPID-PEROXIDATION; COMET ASSAY; (-)-EPIGALLOCATECHIN GALLATE; EPIGALLOCATECHIN GALLATE;
D O I：
10.1016/j.fct.2017.09.012
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Phytochemicals derived from natural plants have been used commonly for the prevention and/or treatment of different diseases due to the belief of their safety. Many plant species synthesize toxic chemicals. New natural chemicals are being discovered but their toxic effects are unknown. Phytochemicals have been regarded as possible antioxidants. But on the other hand it is suggested that various phenolic antioxidants can display pro-oxidant properties at high doses. In this review, the role of some phytochemicals (epigallocathecin gallate, carvacrol, galangin, limonene, lycopene, naringin, puerarin, terpinene, thymol and ursolic acid) on the prevention of DNA damage will be discussed. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：210 / 217
页数：8
相关论文
共 112 条
[21]   FRUIT, VEGETABLES, AND CANCER PREVENTION - A REVIEW OF THE EPIDEMIOLOGIC EVIDENCE [J].
BLOCK, G ;
PATTERSON, B ;
SUBAR, A .
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 1992, 18 (01) :1-29
[22]  
Bravo L, 1998, NUTR REV, V56, P317, DOI 10.1111/j.1753-4887.1998.tb01670.x
[23]   Ursolic acid from apple pomace and traditional plants: A valuable triterpenoid with functional properties [J].
Cargnin, Simone Tasca ;
Gnoatto, Simone Baggio .
FOOD CHEMISTRY, 2017, 220 :477-489
[24]   Effect of Naringin on the DNA Damage Induced by Daunorubicin in Mouse Hepatocytes and Cardiocytes [J].
Carino-Cortes, Raquel ;
Alvarez-Gonzalez, Isela ;
Martino-Roaro, Laura ;
Madrigal-Bujaidar, Eduardo .
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2010, 33 (04) :697-701
[25]   Genetic toxicology evaluation of essential oil of Alpinia zerumbet and its chemoprotective effects against H2O2-induced DNA damage in cultured human leukocytes [J].
Cavalcanti, Bruno C. ;
Ferreira, Jose R. O. ;
Cabral, Igor O. ;
Magalhaes, Hemerson I. F. ;
de Oliveira, Cecilia C. ;
Rodrigues, Felipe A. R. ;
Rocha, Danilo D. ;
Barros, Francisco W. A. ;
da Silva, Cecilia R. ;
Junior, Helio V. N. ;
Canuto, Kirley M. ;
Silveira, Edilberto R. ;
Pessoa, Claudia ;
Moraes, Manoel O. .
FOOD AND CHEMICAL TOXICOLOGY, 2012, 50 (11) :4051-4061
[26]   Antioxidant properties, radical scavenging activity and biomolecule protection capacity of flavonoid naringenin and its glycoside naringin: a comparative study [J].
Cavia-Saiz, Monica ;
Busto, Maria D. ;
Concepcion Pilar-Izquierdo, Maria ;
Ortega, Natividad ;
Perez-Mateos, Manuel ;
Muniz, Pilar .
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2010, 90 (07) :1238-1244
[27]   Endometriotic Implants Regress in Rat Models Treated With Puerarin by Decreasing Estradiol Level [J].
Chen, Yu ;
Chen, Chao ;
Shi, Shufang ;
Han, Jie ;
Wang, Jiaqi ;
Hu, Jingjing ;
Liu, Yuhuan ;
Cai, Zailong ;
Yu, Chaoqin .
REPRODUCTIVE SCIENCES, 2011, 18 (09) :886-891
[28]   Major isoflavonoid contents of the phytoestrogen rich-herb Pueraria mirifica in comparison with Pueraria lobata [J].
Cherdshewasart, Wichai ;
Subtang, Subongkoj ;
Dahlan, Winai .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2007, 43 (02) :428-434
[29]   Puerarin acts through brain serotonergic mechanisms to induce thermal effects [J].
Chueh, FS ;
Chang, CP ;
Chio, CC ;
Lin, MT .
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004, 96 (04) :420-427
[30]   Serum carotenoids and oxidative DNA damage in human lymphocytes [J].
Collins, AR ;
Olmedilla, B ;
Southon, S ;
Granado, F ;
Duthie, SJ .
CARCINOGENESIS, 1998, 19 (12) :2159-2162
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