Are all phytochemicals useful in the preventing of DNA damage?

被引：15

作者：

Bacanli, Merve ^{[1
]}

Aydin, Sevtap ^{[1
]}

Basaran, A. Ahmet ^{[2
]}

Basaran, Nursen ^{[1
]}

机构：

[1] Hacettepe Univ, Fac Pharm, Dept Pharmaceut Toxicol, TR-06100 Ankara, Turkey

[2] Hacettepe Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey

来源：

FOOD AND CHEMICAL TOXICOLOGY | 2017年 / 109卷

关键词：

DNA damage; Phytochemicals; INDUCED OXIDATIVE STRESS; URSOLIC ACID; HUMAN-LYMPHOCYTES; ESSENTIAL OILS; D-LIMONENE; IN-VITRO; LIPID-PEROXIDATION; COMET ASSAY; (-)-EPIGALLOCATECHIN GALLATE; EPIGALLOCATECHIN GALLATE;

D O I：

10.1016/j.fct.2017.09.012

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Phytochemicals derived from natural plants have been used commonly for the prevention and/or treatment of different diseases due to the belief of their safety. Many plant species synthesize toxic chemicals. New natural chemicals are being discovered but their toxic effects are unknown. Phytochemicals have been regarded as possible antioxidants. But on the other hand it is suggested that various phenolic antioxidants can display pro-oxidant properties at high doses. In this review, the role of some phytochemicals (epigallocathecin gallate, carvacrol, galangin, limonene, lycopene, naringin, puerarin, terpinene, thymol and ursolic acid) on the prevention of DNA damage will be discussed. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：210 / 217

页数：8

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