Management of hypertonia in cerebral palsy

被引:45
作者
Nahm, Nickolas J. [1 ]
Graham, H. Kerr [2 ]
Gormley, Mark E., Jr. [3 ]
Georgiadis, Andrew G. [4 ]
机构
[1] Henry Ford Hosp, Dept Orthopaed Surg, Detroit, MI 48202 USA
[2] Royal Childrens Hosp, Dept Orthopaed, Parkville, Vic, Australia
[3] Gillette Childrens Specialty Healthcare, Dept Phys Med & Rehabil, St Paul, MN USA
[4] Gillette Childrens Specialty Healthcare, Dept Orthopaed Surg, St Paul, MN USA
关键词
cerebral palsy; dystonia; hypertonia; spasticity; EVENT MULTILEVEL SURGERY; BOTULINUM-TOXIN-A; RANDOMIZED CONTROLLED-TRIAL; SELECTIVE DORSAL RHIZOTOMY; FEMORAL DEROTATIONAL OSTEOTOMY; LONG-TERM OUTCOMES; INTRATHECAL BACLOFEN; LOWER-LIMB; CHILDREN; SPASTICITY;
D O I
10.1097/MOP.0000000000000567
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Purpose of review The review provides an update on the treatment of hypertonia in cerebral palsy, including physical management, pharmacotherapy, neurosurgical, and orthopedic procedures. Recent findings Serial casting potentiates the effect of Botulinum neurotoxin A injections for spasticity. Deep brain stimulation, intraventricular baclofen, and ventral and dorsal rhizotomy are emerging tools for the treatment of dystonia and/or mixed tone. The long-term results of selective dorsal rhizotomy and the timing of orthopedic surgery represent recent advances in the surgical management of hypertonia. Summary Management of hypertonia in cerebral palsy targets the functional goals of the patient and caregiver. Treatment options are conceptualized as surgical or nonsurgical, focal or generalized, and reversible or irreversible. The role of pharmacologic therapies is to improve function and mitigate adverse effects. Further investigation, including clinical trials, is required to determine the role of deep brain stimulation, intraventricular baclofen, orthopedic procedures for dystonia, and rhizotomy.
引用
收藏
页码:57 / 64
页数:8
相关论文
共 58 条
  • [1] Intraventricular baclofen for dystonia: techniques and outcomes Clinical article
    Albright, A. Leland
    Ferson, Susan S.
    [J]. JOURNAL OF NEUROSURGERY-PEDIATRICS, 2009, 3 (01) : 11 - 14
  • [2] Best-practice surgical techniques for intrathecal baclofen therapy
    Albright, AL
    Turner, M
    Pattisapu, JV
    [J]. JOURNAL OF NEUROSURGERY, 2006, 104 (04) : 233 - 239
  • [3] Albright AL, 2009, IDENTIFICATION TREAT, P429
  • [4] Deep brain stimulation for torsion dystonia in children
    Alterman, Ron L.
    Tagliati, Michele
    [J]. CHILDS NERVOUS SYSTEM, 2007, 23 (09) : 1033 - 1040
  • [5] [Anonymous], COCHRANE DATABASE SY
  • [6] Arnold AS, 1997, DEV MED CHILD NEUROL, V39, P40
  • [7] Responsiveness of the MD-Childhood Rating Scale in dyskinetic cerebral palsy patients undergoing anticholinergic treatment
    Battini, Roberta
    Casarano, Manuela
    Sgandurra, Giuseppina
    Olivieri, Ilaria
    Di Pietro, Roberta
    Romeo, Domenico M.
    Mercuri, Eugenio
    Cioni, Giovanni
    [J]. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 2014, 18 (06) : 698 - 703
  • [8] Infection as a Complication of Intrathecal Baclofen Treatment in Children With Cerebral Palsy
    Bayhan, Ilhan A.
    Sees, Julieanne P.
    Nishnianidze, Tristan
    Rogers, Kenneth J.
    Miller, Freeman
    [J]. JOURNAL OF PEDIATRIC ORTHOPAEDICS, 2016, 36 (03) : 305 - 309
  • [9] An electromyographic protocol that distinguishes spasticity from dystonia
    Beattie, Cammie
    Gormley, Mark
    Wervey, Roy
    Wendorf, Heather
    [J]. JOURNAL OF PEDIATRIC REHABILITATION MEDICINE, 2016, 9 (02) : 125 - 132
  • [10] Blumetti FC, 2016, J PEDIAT ORTHOP