A convenient and simple method for the synthesis of condensed γ-lactams and substituted xanthones from cyclic-1,3-diketones

被引：10

作者：

Chandrasekhar, B ^{[1
]}

Ramadas, SR ^{[1
]}

Ramana, DV ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Chennai 600036, India

来源：

TETRAHEDRON | 2000年 / 56卷 / 32期

关键词：

cyclic-1,3-diketones; O-alkylated derivatives; gamma-lactams; xanthones;

D O I：

10.1016/S0040-4020(00)00484-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A systematic study of alkylation of cyclic-1,3-diones with 2-bromo-6-methoxybenzofuran-3-one was undertaken. Upon condensation in acetic acid with p-substituted aniline the O-alkylated product 3a gave condensed gamma-lactam heterocycle 4. In contrast, the condensation of analogous O-alkylated derivatives 3b and 3e with p-substituted anilines furnished the substituted xanthone derivatives 6 and 7a. The probable mechanism of formation of 4, 6 and 7a was discussed. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：5947 / 5952

页数：6

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