Reactions of gem-Difluorinated Phosphonium Salts Induced by Light

被引：77
|
作者：
Panferova, Liubov I. [1 ]
Tsymbal, Artem V. [1 ,2 ]
Levin, Vitalij V. [1 ]
Struchkova, Marina I. [1 ]
Dilman, Alexander D. [1 ]
机构：
[1] ND Zelinskii Inst Organ Chem, Leninsky Prosp 47, Moscow 119991, Russia
[2] Moscow MV Lomonosov State Univ, Dept Chem, Leninskie Gory 1-3, Moscow 119991, Russia
来源：
ORGANIC LETTERS | 2016年 / 18卷 / 05期
基金：
俄罗斯科学基金会;
关键词：
TRANSFER RADICAL-ADDITION; VISIBLE-LIGHT; PHOTOREDOX CATALYSIS; ORGANOZINC REAGENTS; CARBONYL-COMPOUNDS; DIFLUOROCARBENE; TRIFLUOROMETHYLATION; DIFLUOROMETHYL; ALKENES; BROMODIFLUOROMETHYLATION;
D O I：
10.1021/acs.orglett.6b00117
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
gem-Difluorinated phosphonium salts, which are readily obtained from aldehydes and difluoromethylene phosphobetaine, can serve as a source of radicals under reductive conditions. An iridium complex or Hantzsch ester was used as a one-electron reducing agent when irradiated with visible light. The fluorinated radicals were trapped with various alkenes, leading to products either-via a photoredox cycle (for the iridium catalyst) or via a hydrogen atom transfer (for the Hantzsch ester).
引用
收藏
页码：996 / 999
页数：4
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