Surgical outcomes, bowel habits and quality of life in young patients after ileoanal anastomosis for ulcerative colitis

被引:27
作者
Knod, J. Leslie [1 ]
Holder, Monica [1 ]
Cortez, Alexander R. [1 ]
Martinez-Leo, Bruno [1 ]
Kern, Patricia [1 ]
Saeed, Shehzad [1 ]
Warner, Brad [1 ,2 ,3 ]
Dickie, Belinda [1 ]
Falcone, Richard A. [1 ]
von Allmen, Daniel [1 ]
Frischer, Jason S. [1 ]
机构
[1] Cincinnati Childrens Hosp Med Ctr, 3333 Burnett Ave,MLC 2023, Cincinnati, OH 45229 USA
[2] Washington Univ, Sch Med, One Childrens Pl,Suite 5 s40, St Louis, MO 63110 USA
[3] St Louis Childrens Hosp, One Childrens Pl,Suite 5 s40, St Louis, MO 63110 USA
关键词
pediatric ulcerative colitis; ileoanal pouch anastomosis; outcomes; quality of life; stooling habits; POUCH-ANAL ANASTOMOSIS; STAPLED INTESTINAL ANASTOMOSES; PEDIATRIC-PATIENTS; RESTORATIVE PROCTOCOLECTOMY; FUNCTIONAL OUTCOMES; CHILDREN; DISEASE; QUESTIONNAIRE; COMPLICATIONS; INFANTS;
D O I
10.1016/j.jpedsurg.2016.03.002
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Purpose: We aim to investigate the postoperative outcomes, bowel habits and quality of life (QoL) of younger pediatric ulcerative colitis (UC) patients following surgical intervention compared to an older pediatric population. Methods: Medical records of UC patients after colectomy with ileoanal reconstruction (2002-2013) at our institution were reviewed. Patients/parents completed a QoL, bowel habits and disease course questionnaire. Surgical outcomes, bowel habits and QoL were reported comparing the younger (<= 11 years old, n = 26) to older (>11 years old, n = 38) cohorts. Results: The mean age at colectomy was 7.04 +/- 0.63 years vs 14.71 +/- 0.32 years in the two groups. Patients had a significant (P < 0.001) reduction in stooling frequency after surgery in both age groups and had favorable rates of fecal continence. The frequency of pouchitis and postoperative small bowel obstruction was similar in both cohorts. Dehydration was slightly increased in the younger population but not significant. Anastomotic leak and stricture rates were slightly reduced in younger patients. Postoperative QoL was favorable and similar regardless of age at surgery. Conclusions: Colectomy with ileoanal anastomosis for young children (<= 11 years old) with UC is without increased complications relative to older patients and maintains a postoperative QoL and stool patterns. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:1246 / 1250
页数:5
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