Four acetylcholinesterase genes in the nematode Caenorhabditis elegans

被引：18
|
作者：
Arpagaus, M
Combes, D
Culetto, E
Grauso, M
Fedon, Y
Romani, R
Toutant, JP
机构：
[1] INRA, DCC, Grp Cholinesterases, F-34060 Montpellier 01, France
[2] INRA, F-06606 Antibes, France
[3] Univ Perugia, Dept Expt Med, I-06100 Perugia, Italy
来源：
JOURNAL OF PHYSIOLOGY-PARIS | 1998年 / 92卷 / 5-6期
关键词：
acetylcholinesterases; Ace genes; Caenorhabditis elegans; nematodes;
D O I：
10.1016/S0928-4257(99)80006-0
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Whereas a single gene encodes acetylcholinesterase (AChE) in vertebrates and most insect species, four distinct genes have been cloned and characterized in the nematode Caenorhabditis elegans. We found that ace-1 (mapped to chromosome X) is prominently expressed in muscle cells whereas ace-2 (located on chromosome I) is mainly expressed in neurons. Ace-x and ace-y genes are located in close proximity on chromosome II where they are separated by only a few hundred base pairs. The role of these two genes is still unknown. ((C) Elsevier, Paris).
引用
收藏
页码：363 / 367
页数：5
相关论文
共 50 条
  • [1] Acetylcholinesterase genes in the nematode Caenorhabditis elegans
    Combes, D
    Fedon, Y
    Toutant, JP
    Arpagaus, M
    INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 209, 2001, 209 : 207 - 239
  • [2] Four acetylcholinesterase genes in the nematode Caenorhabditis elegans II.: The third and fourth Ace genes
    Grauso, M
    Culetto, E
    Combes, D
    Fedon, Y
    Toutant, JP
    Arpagaus, M
    STRUCTURE AND FUNCTION OF CHOLINESTERASES AND RELATED PROTEINS, 1998, : 138 - 139
  • [3] Four acetylcholinesterase genes in the nematodes Caenorhabditis elegans and Caenorhabditis briggsae
    Culetto, E
    Grauso, M
    Combes, D
    Fedon, Y
    Romani, R
    Toutant, JP
    Arpagaus, M
    STRUCTURE AND FUNCTION OF CHOLINESTERASES AND RELATED PROTEINS, 1998, : 87 - 92
  • [4] Existence of four acetylcholinesterase genes in the nematodes Caenorhabditis elegans and Caenorhabditis briggsae
    Grauso, M
    Culetto, E
    Combes, D
    Fedon, Y
    Toutant, JP
    Arpagaus, M
    FEBS LETTERS, 1998, 424 (03) : 279 - 284
  • [5] Four acetylcholinesterase genes in the nematode Caenorhabditis elegans I.: Ace-1 and Ace-2
    Combes, D
    Culetto, E
    Grauso, M
    Romani, R
    Fedon, Y
    Toutant, JP
    Arpagaus, M
    STRUCTURE AND FUNCTION OF CHOLINESTERASES AND RELATED PROTEINS, 1998, : 136 - 137
  • [6] The four cdc25 genes from the nematode Caenorhabditis elegans
    Ashcroft, NR
    Kosinski, ME
    Wickramasinghe, D
    Donovan, PJ
    Golden, A
    GENE, 1998, 214 (1-2) : 59 - 66
  • [7] AN ACETYLCHOLINESTERASE-DEFICIENT MUTANT OF THE NEMATODE CAENORHABDITIS-ELEGANS
    JOHNSON, CD
    DUCKETT, JG
    CULOTTI, JG
    HERMAN, RK
    MENEELY, PM
    RUSSELL, RL
    GENETICS, 1981, 97 (02) : 261 - 279
  • [8] MULTIPLE MOLECULAR-FORMS OF ACETYLCHOLINESTERASE IN THE NEMATODE CAENORHABDITIS-ELEGANS
    JOHNSON, CD
    RUSSELL, RL
    JOURNAL OF NEUROCHEMISTRY, 1983, 41 (01) : 30 - 46
  • [9] Acrylamide-responsive genes in the nematode Caenorhabditis elegans
    Hasegawa, Koichi
    Miwa, Satsuki
    Isomura, Kazunori
    Tsutsumiuchi, Kaname
    Taniguchi, Hajime
    Miwa, Johji
    TOXICOLOGICAL SCIENCES, 2008, 101 (02) : 215 - 225
  • [10] HOMEOBOX CONTAINING GENES IN THE NEMATODE CAENORHABDITIS-ELEGANS
    HAWKINS, NC
    MCGHEE, JD
    NUCLEIC ACIDS RESEARCH, 1990, 18 (20) : 6101 - 6106
12345