Scratching the surface: a role of pain-sensing TRPA1 in itch

被引:26
|
作者
Xiao, Bailong [1 ]
Patapoutian, Ardem [2 ]
机构
[1] Scripps Res Inst, Dept Cell Biol, La Jolla, CA 92037 USA
[2] Novartis Res Fdn, Genom Inst, San Diego, CA USA
关键词
COLD; MECHANISMS; CHANNELS;
D O I
10.1038/nn.2813
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The molecular mechanisms of itch, particularly histamine-independent itch, are unclear. Wilson et al. report that TRPA1, an ion channel critical for pain sensation, also functions as an essential component of itch transduction.
引用
收藏
页码:540 / 542
页数:4
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