Targeting the p27kip1/cdk4/cdk2/Rb axis in breast cancer using a peptidomimetic of Brk's SH3 domain

被引：0
|
作者：
Blain, Stacy W.
Quinones, Jason
Patel, Priyank
Tsiperson, Vladislav
Gottesman, Susan
Somma, Jonathan
Wu, Yun
机构：
来源：
CANCER RESEARCH | 2017年 / 77卷
关键词：
D O I：
10.1158/1538-7445.AM2017-2348
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2348
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Implication of malignancy and prognosis of p27kip1, cyclin E, and Cdk2 expression in epithelial ovarian tumors
    Sui, L
    Dong, YY
    Ohno, M
    Sugimoto, K
    Tai, YJ
    Hando, T
    Tokuda, M
    GYNECOLOGIC ONCOLOGY, 2001, 83 (01) : 56 - 63
  • [22] HBx upregulated lncRNA facilitates HCC tumor growth via suppression of p27Kip1/CDK2
    Hu, J. -J.
    Qiu, X. M.
    Qiao, F. C.
    Song, W.
    Wu, H. Z.
    Gong, P. H.
    Shen, X. H.
    Fan, H.
    ANNALS OF ONCOLOGY, 2015, 26 : 64 - 64
  • [23] p27kip1和cdk2在胃癌中的表达及其意义
    张世同
    徐志林
    河南肿瘤学杂志, 2002, (06) : 407 - 408+493
  • [24] Disordered p27Kip1 exhibits intrinsic structure resembling the Cdk2/cyclin A-bound conformation
    Sivakolundu, SG
    Bashford, D
    Kriwacki, RW
    JOURNAL OF MOLECULAR BIOLOGY, 2005, 353 (05) : 1118 - 1128
  • [25] Tyrosine phosphorylation of p27kip1 regulates the activity of cyclin D-cdk4 complexes in breast cancer
    Patel, Priyank
    Shetyn, Elina
    Gomez, Cindy
    Gottesman, Susan R. S.
    Tyner, Angela
    Asbach, Benedikt
    Wagner, Ralf
    Blain, Stacy W.
    CANCER RESEARCH, 2015, 75
  • [26] XLGαolf regulates expression of p27Kip1 in a CSN5 and CDK2 dependent manner
    Akita, Kazumasa
    Takahashi, Yasuhiko
    Takata, Naoko
    Hashimoto, Michiru
    Kataoka, Masaki
    Tomigahara, Yoshitaka
    Saito, Koichi
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2011, 416 (3-4) : 385 - 390
  • [27] Relationship between the expressions of CDK2, p27kip1 proteins and non-small cell lung cancer of XuanWei
    Huang Yunchao
    Li Xiaoming
    Yang Kaiyun
    Zhao Guangqiang
    Gao Jia
    Wang Kun
    Ye Lianhua
    Lei Yujie
    JOURNAL OF THORACIC ONCOLOGY, 2009, 4 (09) : S869 - S869
  • [28] Involvement of p27kip1 and cyclin D3 in the regulation of cdk2 activity during skeletal muscle differentiation
    Chu, CY
    Lim, RW
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2000, 1497 (02): : 175 - 185
  • [29] p27Kip1 V109G as a biomarker for CDK4/6 inhibitors indication in hormone receptor-positive breast cancer
    Mouron, Silvana
    Bueno, Maria J.
    Munoz, Manuel
    Torres, Raul
    Rodriguez, Sandra
    Apala, Juan, V
    Silva, Jorge
    Sanchez-Bayona, Rodrigo
    Manso, Luis
    Guerra, Juan
    Rodriguez-Lajusticia, Laura
    Malon, Diego
    Malumbres, Marcos
    Quintela-Fandino, Miguel
    JNCI CANCER SPECTRUM, 2023, 7 (02)
  • [30] PTK6/BRK modulates tyrosine phosphorylation of p27Kip1 and the activity of the oncogene cyclin D-cdk4.
    Blain, Stacy W.
    Gomez, Cindy
    Shteyn, Elina
    Patel, Priyank
    Gottesman, Susan R. S.
    Asbach, Benedikt
    Wagner, Ralf
    Tyner, Angela L.
    CANCER RESEARCH, 2013, 73 (08)
12345