Light-induced cytotoxicity of a photochromic spiropyran

被引:42
作者
Nilsson, Jesper R. [3 ]
Li, Shiming [3 ]
Onfelt, Bjorn [1 ,2 ]
Andreasson, Joakim [3 ]
机构
[1] Royal Inst Technol, Dept Appl Phys, Div Cell Phys, S-10691 Stockholm, Sweden
[2] Karolinska Inst, Dept Microbiol Tumour & Cell Biol, S-17177 Stockholm, Sweden
[3] Chalmers, Dept Chem & Biol Engn, S-41296 Gothenburg, Sweden
基金
瑞典研究理事会; 欧洲研究理事会;
关键词
LOCK-IN DETECTION; LIVING CELLS; APOPTOSIS; NANOPARTICLES; FLUORESCENCE; PHOTOCONTROL; PROTEINS; SWITCH;
D O I
10.1039/c1cc13561a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this work we present a novel water soluble spiropyran photoswitch that can be photonically activated inside live cells from a form that has no significant effect on the cellular survival to a form that induces a dramatic toxic response.
引用
收藏
页码:11020 / 11022
页数:3
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