Functional near-infrared fluorescent probes

被引：229

作者：

Kiyose, Kazuki ^{[1
,2
]}

Kojima, Hirotatsu ^{[1
,2
]}

Nagano, Tetsuo ^{[1
,2
]}

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan

[2] JST, CREST, Kawaguchi, Saitama 3320012, Japan

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2008年 / 3卷 / 03期

关键词：

biosensors; electron transfer; fluorescent probes; functional probes; ratiometric probes;

D O I：

10.1002/asia.200700267

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Near-infrared (NIR) fluorescent probes have attracted much attention, but despite the availability of various NIR fluorophores, only a few functional NIR probes, that is, probes whose absorption and/or fluorescence spectra change upon specific reaction with biomolecules, have been developed. However, functional probes operating in the NIR range that can be targeted to protons, metal ions, nitric oxide, P-galactosidase, and cellular stress markers are expected to be effective for fluorescence imaging in vivo. This Focus Review concentrates on these functional NIR probes themselves, not their applications.

引用

页码：506 / 515

页数：10

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