Inflammatory effect on the gastrointestinal system associated with COVID-19

被引:11
作者
Delgado-Gonzalez, Paulina [1 ]
Gonzalez-Villarreal, Carlos A. [2 ]
Roacho-Perez, Jorge A. [1 ]
Quiroz-Reyes, Adriana G. [1 ]
Islas, Jose Francisco [1 ]
Delgado-Gallegos, Juan Luis [1 ]
Arellanos-Soto, Daniel [1 ]
Galan-Huerta, Kame A. [1 ]
Garza-Trevino, Elsa N. [1 ]
机构
[1] UANL, Dept Bioquim & Med Mol, Monterrey 64610, Nuevo Leon, Mexico
[2] Univ Monterrey, UDEM Vicerrectoria Ciencias Salud, Monterrey 66238, Nuevo Leon, Mexico
关键词
SARS-CoV-2; Gastrointestinal symptoms; COVID-19; Gastrointestinal system; CORONAVIRUS; SARS-COV-2; EFFICACY; CHLOROQUINE; ACE2;
D O I
10.3748/wjg.v27.i26.4160
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) that causes coronavirus disease-2019 (COVID-19) has provoked a global pandemic, mainly affecting the respiratory tract; however, a percentage of infected individuals can develop gastrointestinal (GI) symptoms. Some studies describe the development of GI symptoms and how they affect the progression of COVID-19. In this review, we summarize the main mechanisms associated with gut damage during infection by SARS-CoV-2 as well as other organs such as the liver and pancreas. Not only are host factors associated with severe COVID-19 but intestinal microbiota dysbiosis is also observed in patients with severe disease.
引用
收藏
页码:4160 / 4171
页数:12
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