Progress in Corneal Stromal Repair: From Tissue Grafts and Biomaterials to Modular Supramolecular Tissue-Like Assemblies

被引：53
作者：
Kumar, Pramod [1 ,2 ]
Pandit, Abhay [2 ]
Zeugolis, Dimitrios I. [1 ,2 ]
机构：
[1] Natl Univ Ireland Galway NUI Galway, Regenerat Modular & Dev Engn Lab REMODEL, Biosci Res Bldg, Galway, Ireland
[2] Natl Univ Ireland Galway NUI Galway, Ctr Res Med Devices CURAM, Biosci Res Bldg, Galway, Ireland
来源：
ADVANCED MATERIALS | 2016年 / 28卷 / 27期
基金：
爱尔兰科学基金会;
关键词：
corneal stromal; corneal keratocytes; tissue grafts; biomaterials; modular engineering; AMNIOTIC MEMBRANE TRANSPLANTATION; RECOMBINANT HUMAN COLLAGEN; RESPONSIVE CULTURE DISHES; MESENCHYMAL STEM-CELLS; ARTIFICIAL EXTRACELLULAR-MATRIX; KERATAN SULFATE PROTEOGLYCAN; HYALURONIC-ACID HYDROGELS; GROWTH-FACTOR EXPRESSION; IN-VITRO; KERATOCYTE PHENOTYPE;
D O I：
10.1002/adma.201503986
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Corneal injuries and degenerative conditions have major socioeconomic consequences, given that in most cases, they result in blindness. In the quest of the ideal therapy, tissue grafts, biomaterials, and modular engineering approaches are under intense investigation. Herein, advancements and shortfalls are reviewed and future perspectives for these therapeutic strategies discussed.
引用
收藏
页码：5381 / 5399
页数：19
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