Periprocedural Myocardial Infarction: Review and Classification

被引：34

作者：

Hanna, Elias B. ^{[1
]}

Hennebry, Thomas A. ^{[1
]}

机构：

[1] Univ Oklahoma, Hlth Sci Ctr, Dept Med, Cardiovasc Sect, Oklahoma City, OK 73104 USA

来源：

CLINICAL CARDIOLOGY | 2010年 / 33卷 / 08期

关键词：

PERCUTANEOUS CORONARY INTERVENTION; VEIN GRAFT INTERVENTION; MB ENZYME ELEVATION; DRUG-ELUTING STENTS; TROPONIN-I; CK-MB; PROGNOSTIC-SIGNIFICANCE; RANDOMIZED-TRIAL; POOLED ANALYSIS; ARTERY-DISEASE;

D O I：

10.1002/clc.20819

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Technical and pharmacologic advances have reduced the occurrence of large periprocedural myocardial infarction (PMI) after percutaneous coronary interventions (PCI), but PMI still occurs in 6% to 18% of the cases and is associated with impaired short- and long-term survival. PMI might be due to side branch closure or flow-limiting dissection, but is most often diagnosed after apparently uncomplicated PCI and is due to atheroembolization into the microcirculation. Various definitions of PMI are used in clinical trials, but a rise in creatine kinase-MB greater than 3 to 8 times the upper limit of normal is consistently associated with worse prognosis, particularly as it reflects a more extensive and unstable atherosclerotic burden. On the other hand, data regarding the independent prognostic value of periprocedural troponin increase are conflicting. Some data suggest that PM! has a better prognosis than a spontaneously occurring myocardial infarction, and that its incidence is reduced with aggressive antiplatelet and statin therapy.

引用

页码：476 / 483

页数：8

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