Bioinformatic Approaches for Identification of A-to-I Editing Sites

被引：15

作者：

Eisenberg, Eli ^{[1
]}

机构：

[1] Tel Aviv Univ, Raymond & Beverly Sack ler Sch Phys & Astron, IL-69978 Tel Aviv, Israel

来源：

ADENOSINE DEAMINASES ACTING ON RNA (ADARS) AND A-TO-I EDITING | 2012年 / 353卷

关键词：

A-to-I RNA editing; Alu repeats; Bioinformatics; Deep sequencing; SELECTIVE ADENOSINE DEAMINATION; TIME PCR METHOD; MESSENGER-RNA; HUMAN TRANSCRIPTOME; INOSINE RNA; ALU REPEATS; EDITED RNAS; NUCLEAR RETENTION; ADAR DEAMINASES; SNP DATABASE;

D O I：

10.1007/82_2011_147

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The first discoveries of mammalian A-to-I RNA editing have been serendipitous. In conjunction with the fast advancement in sequencing technology, systematic methods for prediction and detection of editing sites have been developed, leading to the discovery of thousands of A-to-I editing sites. Here we review the state-of-the-art of these methods and discuss future directions.

引用

页码：145 / 162

页数：18

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