Effect of high-density lipoproteins on ADP-induced platelet aggregation in plasma

被引：3

作者：

Vlasova, II ^{[1
]}

Azizova, OA ^{[1
]}

机构：

[1] Minist Hlth, Inst Physicochem Med, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1998年 / 126卷 / 08期

关键词：

platelets; platelet-rich plasma; aggregation; high-density lipoproteins; oxidation;

D O I：

10.1007/BF02446909

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Autooxidized high-density lipoproteins (HDL2) inhibit ADP-induced platelet aggregation in platelet-rich plasma. Platelet aggregation in the presence of native HDL2 and HDL3 and autooxidized HDL3 does not differ from the control (plasma with buffer). A conclusion is made on the important role of autooxidized HDL2 as a thrombogenesis-inhibiting factor in atherosclerosis.

引用

页码：783 / 786

页数：4

共 14 条

[1] PLATELET ACTIVATION BY OXIDATIVELY MODIFIED LOW-DENSITY LIPOPROTEINS
ARDLIE, NG
SELLEY, ML
SIMONS, LA
[J]. ATHEROSCLEROSIS, 1989, 76 (2-3) : 117 - 124
[2] CURTISS LK, 1984, BLOOD, V64, P365
[3] DESAI K, 1989, J LIPID RES, V30, P831
[4] FEOKTISTOV I A, 1991, Byulleten' Eksperimental'noi Biologii i Meditsiny, V111, P485
[5] PLATELET-AGGREGATION - THE USE OF OPTICAL-DENSITY FLUCTUATIONS TO STUDY MICROAGGREGATE FORMATION IN PLATELET SUSPENSION
GABBASOV, ZA
POPOV, EG
GAVRILOV, IY
POZIN, EY
[J]. THROMBOSIS RESEARCH, 1989, 54 (03) : 215 - 223
[6] Alterations in the physicochemical characteristics of low and high density lipoproteins after lipolysis with phospholipase A(2). A spin-label study
Gorshkova, IN
Menschikowski, M
Jaross, W
[J]. BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM, 1996, 1300 (02): : 103 - 113
[7] THE AGGREGATION OF ISOLATED HUMAN-PLATELETS IN THE PRESENCE OF LIPOPROTEINS AND PROSTACYCLIN
HASSALL, DG
OWEN, JS
BRUCKDORFER, KR
[J]. BIOCHEMICAL JOURNAL, 1983, 216 (01) : 43 - 49
[8] ITZAKI RF, 1964, ANAL BIOCHEM, V9, P401
[9] Lindgren F. T., 1975, ANAL LIPIDS LIPOPROT, P204
[10] MENTA JL, 1996, J LAB CLIN MED, V127, P287

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