A numerical study of the blocking of migraine by Rolando sulcus

被引：9

作者：

Grenier, E. ^{[1
]}

Dronne, M. A. ^{[2
,3
,4
,5
]}

Descombes, S. ^{[1
]}

Gilquin, H. ^{[1
]}

Jaillard, A. ^{[6
]}

Hommel, M. ^{[6
]}

Boissel, J. -P. ^{[2
,3
,4
,5
]}

机构：

[1] Ecole Normale Super Lyon, Unite Math Pures & Appl, UMR 5669, F-69364 Lyon, France

[2] Univ Lyon, F-69003 Lyon, France

[3] Univ Lyon 1, ISPB, F-69003 Lyon, France

[4] CNRS, UMR5558, F-69003 Lyon, France

[5] Inst Med Theor, F-69003 Lyon, France

[6] CHU Grenoble, F-38043 Grenoble, France

来源：

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY | 2008年 / 97卷 / 01期

关键词：

numerical modeling; migraine; Rolando sulcus;

D O I：

10.1016/j.pbiomolbio.2007.10.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Migraine with aura, is a complex phenomena, which remains still not completely understood. A striking fact is that its clinical. manifestations may change from one patient to another. Migraine with aura may only consist in visual hallucinations, but may as well go on to temporary aphasy. However, for all the patients it always stops before it goes from area 3 to area 4, thus just before crossing Rolando sulcus. In this paper, we give arguments showing that the detailed geometry of Rolando sulcus in human cortex may by itself explain that migraine attack never crosses Rolando sulcus. (c) 2007 Published by Elsevier Ltd.

引用

页码：54 / 59

页数：6

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