Severe new seizures after initiation of vagus nerve stimulation therapy

被引：2

作者：

Murr, Najib I. ^{[1
]}

Azar, Nabil J. ^{[1
]}

机构：

[1] Vanderbilt Univ, Med Ctr, Dept Neurol, Nashville, TN 37232 USA

来源：

EPILEPSY & BEHAVIOR | 2011年 / 22卷 / 02期

关键词：

Vagus nerve stimulator; Paradoxical seizures; Acute partial seizures; Antiepileptic drugs; ANTIEPILEPTIC DRUGS; EPILEPSY; AGGRAVATION;

D O I：

10.1016/j.yebeh.2011.06.032

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Vagus nerve stimulation is considered to be a safe and effective adjunctive therapy for patients with drug-resistant epilepsy. Contrary to some antiepileptic drugs, vagus nerve stimulation is not known to precipitate or aggravate new or preexisting seizures. We describe the emergence of a new type of disabling, recurrent partial seizure immediately after initiation of vagus nerve stimulation in a 51-year-old man with a known history of refractory partial epilepsy. Discontinuation of vagus nerve stimulation therapy and multiple antiepileptic drug interventions were required to abort these unexpected new seizures. We conclude that vagus nerve stimulation may induce paradoxical seizures, similarly to some antiepileptic drugs. (C) 2011 Elsevier Inc. All rights reserved.

引用

页码：398 / 400

页数：3

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