N-Heterocyclic Carbene Catalyzed Photooxidation: Intramolecular Cross Dehydrogenative Coupling of Tetrahydroisoquinoline-Tethered Aldehydes

被引：27
作者：
Gao, Zhong-Hua [1 ]
Xia, Zi-Hao [1 ,2 ]
Dai, Lei [1 ,2 ]
Ye, Song [1 ,2 ]
机构：
[1] Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, CAS Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2020年 / 362卷 / 09期
基金：
中国国家自然科学基金;
关键词：
N-heterocyclic carbene; photocatalysis; organocatalysis; oxidation; dehydrogenative coupling; COOPERATIVE CATALYSIS; ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC-SYNTHESIS; DUAL CATALYSIS; KINETIC RESOLUTION; TERTIARY-AMINES; DELTA-LACTONES; C-C; PHOTOREDOX; ENALS;
D O I：
10.1002/adsc.202000164
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
An N-heterocyclic carbene catalyzed photooxidation reaction via intramolecular cross dehydrogenative coupling of tetrahydroisoquinoline-tethered aldehydes was developed, giving the corresponding oxidative cyclization products in moderate to good yields. This reaction features mild conditions with oxygen as the terminal oxidant in the absence of photocatalyst.
引用
收藏
页码：1819 / 1824
页数：6
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