Steryl epoxide, secobutanolide and butanolides from the stem wood of Machilus zuihoensis

被引：34

作者：

Cheng, MJ

Tsai, IL

Lee, SJ

Jayaprakasam, B

Chen, IS ^{[1
]}

机构：

[1] Kaohsiung Med Univ, Grad Inst Pharmaceut Sci, Kaohsiung 807, Taiwan

[2] Natl Hlth Res Inst, Div Biotechnol & Pharmaceut Res, Taipei 114, Taiwan

来源：

PHYTOCHEMISTRY | 2005年 / 66卷 / 10期

关键词：

Machilus zuihoensis; Lauraceae; stem wood; steryl epoxide; machillene; secobutanolide; secomahubanolide; butanolides; zuihoenalide; 3-(1-methoxy-octadecyl)-5-methylene-5H-furan-2-one; cytotoxicity;

D O I：

10.1016/j.phytochem.2005.03.020

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A steryl epoxide, machillene (1), a secobutanolide, secomahubanolide (2), and two butanolides, zuihoenalide (3), and 3-(1-methoxyoctadecyl)-5-methylene-5H-furan-2-one,(4), together with 12 known compounds, were isolated from stem wood of Machihis zuihoensis. Their structures were determined by means of spectroscopic analyses. Machillene (1) showed cytotoxic activity against NUGC-3 and HONE-1 cancer cell lines in vitro. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1180 / 1185

页数：6

共 24 条

[1] Chemical constituents from Annona glabra III [J].