Streptococcal emm types associated with T-agglutination types and the use of conserved emm gene restriction fragment patterns for subtyping group A streptococci

被引：38

作者：

Beall, B ^{[1
]}

Facklam, RR ^{[1
]}

Elliott, JA ^{[1
]}

Franklin, AR ^{[1
]}

Hoenes, T ^{[1
]}

Jackson, D ^{[1
]}

Laclaire, L ^{[1
]}

Thompson, T ^{[1
]}

Viswanathan, R ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 1998年 / 47卷 / 10期

关键词：

D O I：

10.1099/00222615-47-10-893

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The T-agglutination types were determined for a diverse collection of 1531 group A streptococci for which the 5' M protein gene (emm) sequences had been analysed. The majority of the T-agglutination types correlated with previously seen M/emm/T-type associations; however, several new associations were found. Analysis of a subset of this collection - which included 1157 clinical isolates with multiply encountered emm types - found that emm amplicon restriction profiles of isolates sharing identical T types and opacity factor phenotypes are useful for detecting groups of isolates with identical emm genes. Many emm genes of known 5' sequence display a highly conserved restriction pattern amongst clinical isolates widely separated both geographically and temporally.

引用

页码：893 / 898

页数：6

共 16 条

[1] Survey of emm gene sequences and T-antigen types from systemic Streptococcus pyogenes infection isolates collected in San Francisco, California; Atlanta, Georgia; and Connecticut in 1994 and 1995 [J].