Pituitary carcinoma:: A clinicopathological review

被引:94
作者
Scheithauer, BW
Kurtkaya-Yapicier, Ö
Kovacs, KT
Young, WF
Lloyd, RV
机构
[1] Mayo Clin, Dept Pathol & Lab Med, Rochester, MN 55901 USA
[2] Marmara Univ, Inst Neurol Sci, Istanbul, Turkey
[3] Univ Toronto, St Michaels Hosp, Dept Lab Med & Pathobiol, Toronto, ON M5B 1W8, Canada
[4] Mayo Clin, Dept Endocrinol, Rochester, MN USA
关键词
diagnosis; genetics; metastasis; pituitary carcinoma; treatment;
D O I
10.1227/01.NEU.0000157926.72826.DB
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
PITUITARY CARCINOMAS ARE rare tumors; less than 100 well-documented cases have been reported to date. Such tumors are aggressive and associated with a high mortality rate. The molecular events leading to the development of pituitary carcinomas are largely unknown. Recent studies have only begun to shed light on the probable mechanisms of tumor initiation and progression. A review of the clinicopathological and molecular genetic characteristics of pituitary carcinomas is presented.
引用
收藏
页码:1066 / 1074
页数:9
相关论文
共 81 条
[1]   Loss of expression of the growth inhibitory gene GADD45γ, in human pituitary adenomas, is associated with CpG island methylation [J].
Bahar, A ;
Bicknell, JE ;
Simpson, DJ ;
Clayton, RN ;
Farrell, WE .
ONCOGENE, 2004, 23 (04) :936-944
[2]  
Baylin SB, 1998, ADV CANCER RES, V72, P141
[3]   GONADOTROPIC PITUITARY CARCINOMA - CASE-REPORT [J].
BEAUCHESNE, P ;
TROUILLAS, J ;
BARRAL, F ;
BRUNON, J .
NEUROSURGERY, 1995, 37 (04) :810-815
[4]   Pituitary tumours are multiclonal from the outset: evidence from a case with dural metastases [J].
Buch, H ;
El-Hadd, T ;
Bicknell, J ;
Simpson, SJ ;
Farrell, WE ;
Clayton, RN .
CLINICAL ENDOCRINOLOGY, 2002, 56 (06) :817-822
[5]  
Clayton RN, 2001, BRAIN PATHOL, V11, P313
[6]   Pituitary basophilism associated with a basophil carcinoma of the anterior lobe of the pituitary gland. [J].
Cohen, H ;
Dible, JH .
BRAIN, 1936, 59 :395-407
[7]   Novel patterns of gene expression in pituitary adenomas identified by complementary deoxyribonucleic acid microarrays and quantitative reverse transcription-polymerase chain reaction [J].
Evans, CO ;
Young, AN ;
Brown, MR ;
Brat, DJ ;
Parks, JS ;
Neish, AS ;
Oyesiku, NM .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (07) :3097-3107
[8]   Epigenetic change in pituitary tumorigenesis [J].
Farrell, WE ;
Clayton, RN .
ENDOCRINE-RELATED CANCER, 2003, 10 (02) :323-330
[9]   Corticotroph carcinoma presenting as a silent corticotroph adenoma [J].
William E. Farrell ;
Anthony P. Coll ;
Richard N. Clayton ;
Philip E. Harris .
Pituitary, 2003, 6 (1) :41-47
[10]   CARCINOMA OF THE PITUITARY GLAND WITH METASTASES TO THE LIVER IN A CASE OF CUSHINGS SYNDROME [J].
FORBES, W .
JOURNAL OF PATHOLOGY AND BACTERIOLOGY, 1947, 59 (1-2) :137-&