Interfrontal commissural abnormality, in schizophrenia: Tractography-assisted callosal parcellation

被引：17

作者：

Miyata, Jun ^{[1
]}

Hirao, Kazuyuki ^{[1
]}

Namiki, Chihiro ^{[1
,2
]}

Fukuyama, Hidenao ^{[2
]}

Okada, Tsutomu ^{[3
]}

Miki, Yukio ^{[3
]}

Hayashi, Takuji ^{[1
]}

Murai, Toshiya ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Med, Dept Neuropsychiat, Kyoto 6068507, Japan

[2] Kyoto Univ, Grad Sch Med, Human Brain Res Ctr, Kyoto 6068507, Japan

[3] Kyoto Univ, Grad Sch Med, Dept Diagnost Imaging & Nucl Med, Kyoto 6068507, Japan

来源：

SCHIZOPHRENIA RESEARCH | 2007年 / 97卷 / 1-3期

关键词：

schizophrenia; white matter; diffusion tensor imaging; tractography;

D O I：

10.1016/j.schres.2007.07.032

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Previous studies have indicated abnormal fiber connectivity of the corpus callosurn (CC) in schizophrenia. This study investigated whether the interfrontal commissural region of the CC is decreased in schizophrenia, by partitioning the CC using a functio-anatomically relevant internal landmark derived from tractographic analysis of diffusion tensor imaging (DTI). T1 weighted and DTI images were acquired by 3T-MRI. Using tractography, the interfrontal commissural region (anterior part) was partitioned from the rest of the CC in 40 schizophrenia patients and 36 healthy controls. Schizophrenia patients showed smaller anterior/total CC length and area rates. These results suggested interfrontal hypoconnectivity in schizophrenia. (C) 2007 Elsevier B.V. All tights reserved.

引用

页码：236 / 241

页数：6

共 37 条

[1]

Basser PJ, 2000, MAGNET RESON MED, V44, P625, DOI 10.1002/1522-2594(200010)44:4<625::AID-MRM17>3.0.CO

[2]

2-O

[3] MR DIFFUSION TENSOR SPECTROSCOPY AND IMAGING [J].

BASSER, PJ ;

MATTIELLO, J ;

LEBIHAN, D .

BIOPHYSICAL JOURNAL, 1994, 66 (01) :259-267

[4] On the use of water phantom images to calibrate and correct eddy current induced artefacts in MR diffusion tensor imaging [J].

Bastin, ME ;

Armitage, PA .

MAGNETIC RESONANCE IMAGING, 2000, 18 (06) :681-687

[5] Probabilistic diffusion tractography with multiple fibre orientations: What can we gain? [J].

Behrens, T. E. J. ;

Berg, H. Johansen ;

Jbabdi, S. ;

Rushworth, M. F. S. ;

Woolrich, M. W. .

NEUROIMAGE, 2007, 34 (01) :144-155

[6] Does dysplasia cause anatomical dysconnectivity in schizophrenia? [J].

Bullmore, ET ;

Woodruff, PWR ;

Wright, IC ;

Rabe-Hesketh, S ;

Howard, RJ ;

Shuriquie, N ;

Murray, RM .

SCHIZOPHRENIA RESEARCH, 1998, 30 (02) :127-135

[7] Schizophrenia as a transcallosal misconnection syndrome [J].

Crow, TJ .

SCHIZOPHRENIA RESEARCH, 1998, 30 (02) :111-114

[8] TOPOGRAPHY OF THE HUMAN CORPUS-CALLOSUM [J].

DELACOSTE, MC ;

KIRKPATRICK, JB ;

ROSS, ED .

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1985, 44 (06) :578-591

[9]

First M, 2017, Structured Clinical Interview for DSM-5 Personality Disorders (SCID-5-PD)

[10]

First M.B., 1998, STRUCTURED CLIN INTE

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