Torilin, a sesquiterpene from Torilis japonica, reverses multidrug-resistance in cancer cells

被引：31
作者：
Kim, SE
Kim, YH
Kim, YC
Lee, JJ
机构：
[1] Nat Prod Biosynth RU, Korea Res Inst Biosci & Biotechnol, Taejon 305600, South Korea
[2] Seoul Natl Univ, Coll Pharm, Seoul, South Korea
[3] Chungnam Natl Univ, Coll Pharm, Taejon, South Korea
来源：
PLANTA MEDICA | 1998年 / 64卷 / 04期
关键词：
Torilis joponica; Umbelliferae; torilin; sesquiterpene; multidrug-resistance (MDR);
D O I：
10.1055/s-2006-957445
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A sesquiterpene compound reversing multidrug-resistance in cancer cells was isolated from the fruits of Torilis japonica and the structure was identified as torilin. Torilin potentiated the cytotoxicities of adriamycin, vinblastine, taxol and colchicine against multidrug-resistant KB-V1 and MCF7/ADR cells.
引用
收藏
页码：332 / 334
页数：3
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