Clinical diagnostic utility of contrast-enhanced three-dimensional fluid-attenuated inversion recovery for selection of brain biopsy sites in neurosarcoidosis: A case report

被引:1
作者
Ueno, Tatsuya [1 ]
Desaki, Rie [1 ]
Kon, Tomoya [1 ]
Haga, Rie [1 ]
Nunomura, Jin-ichi [1 ]
Murakami, Kensuke [2 ]
Tomiyama, Masahiko [1 ]
机构
[1] Aomori Prefectural Cent Hosp, Dept Neurol, 2-1-1 Higashi Tsukurimichi, Aomori 0308551, Japan
[2] Aomori Prefectural Cent Hosp, Dept Neurosurg, Aomori, Japan
关键词
Neurosarcoidosis; Fluid-attenuated inversion recovery; Three-dimensional image; Contrast media; Biopsy;
D O I
10.1016/j.clineuro.2018.08.006
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Neurosarcoidosis is difficult to diagnose, because definite diagnosis requires detailed histology of the central nervous system. Three-dimensional contrast-enhanced fluid-attenuated inversion recovery (CE-FLAIR) is more useful for detecting leptomeningeal lesions compared with 3D CE-Tl weighted imaging. However, the clinical diagnostic utility of 3D CE-FLAIR for neurosarcoidosis is unclear. We describe a case of a 46-year-old Japanese woman who was admitted to our department due to chronic headache with fever and diplopia. Using 3D CE-FLAIR, we performed brain biopsy from right cerebellar lesion. The histological examination revealed typical non-caseating granulomas, indicating neurosarcoidosis. Our findings suggest that 3D CE-FLAIR may detect leptomeningeal lesions that are candidates for biopsy in chronic meningitis undetermined etiology.
引用
收藏
页码:101 / 104
页数:4
相关论文
共 5 条
[1]   Leptomeningeal Infiltration, the Hallmark of Neurosarcoidosis [J].
Ait-Oufella, Hafid ;
Gabignon, Caroline ;
Capron, Jean ;
Mekinian, Arsene .
AMERICAN JOURNAL OF MEDICINE, 2017, 130 (08) :E331-E332
[2]   Cerebrospinal fluid changes after intravenous injection of gadolinium chelate: assessment by FLAIR MR imaging [J].
Bozzao, A ;
Floris, R ;
Fasoli, F ;
Fantozzi, LM ;
Colonnese, C ;
Simonetti, G .
EUROPEAN RADIOLOGY, 2003, 13 (03) :592-597
[3]   Clinical features, treatment and outcome in neurosarcoidosis: systematic review and meta-analysis [J].
Fritz, Daan ;
van de Beek, Diederik ;
Brouwer, Matthijs C. .
BMC NEUROLOGY, 2016, 16
[4]   Comparison of the Added Value of Contrast-Enhanced 3D Fluid-Attenuated Inversion Recovery and Magnetization-Prepared Rapid Acquisition of Gradient Echo Sequences in Relation to Conventional Postcontrast T1-Weighted Images for the Evaluation of Leptomeningeal Diseases at 3T [J].
Fukuoka, H. ;
Hirai, T. ;
Okuda, T. ;
Shigematsu, Y. ;
Sasao, A. ;
Kimura, E. ;
Hirano, T. ;
Yano, S. ;
Murakami, R. ;
Yamashita, Y. .
AMERICAN JOURNAL OF NEURORADIOLOGY, 2010, 31 (05) :868-873
[5]   Neurosarcoidosis: a clinical dilemma [J].
Hoitsma, E ;
Faber, CG ;
Drent, M ;
Sharma, OP .
LANCET NEUROLOGY, 2004, 3 (07) :397-407