Au Nanowire-on-Film SERRS Sensor for Ultrasensitive Hg2+ Detection

被引：73

作者：

Kang, Taejoon ^{[1
]}

Yoo, Seung Min ^{[2
]}

Yoon, Ilsun ^{[1
]}

Lee, Sangyeop ^{[2
,3
]}

Choo, Jaebum ^{[3
]}

Lee, Sang Yup

Kim, Bongsoo ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Chem, Taejon 305701, South Korea

[2] Korea Adv Inst Sci & Technol, Dept Chem & Biomol Engn, BK21 Program, Taejon 305701, South Korea

[3] Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2011年 / 17卷 / 07期

关键词：

DNA; gold; mercury; nanowires; surface-enhanced Raman scattering; ENHANCED RAMAN-SCATTERING; ANODIC-STRIPPING VOLTAMMETRY; SINGLE-MOLECULE; DNA DETECTION; QUANTUM DOTS; METAL-IONS; MERCURY; NANOPARTICLES; SPECTROSCOPY; APTAMER;

D O I：

10.1002/chem.201001663

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report an ultrasensitive and selective single nanowire-on-film (SNOF) surface-enhanced resonance Raman scattering (SERRS) sensor for Hg2+ detection based on structure-switching double stranded DNAs (dsDNAs). Binding of Hg2+ induces conformational changes of the dsDNAs and let a Raman reporter get close to the SNOF structure, thereby turning on SERRS signal. The well-defined SNOF structure provides a detection limit of 100 pm with improved accuracy in Hg2+ detection. This sensor is stable over a considerable amount of time and reusable after simple treatment. Since this SNOF sensor is composed of a single Au NW on a film, development of a multiplex sensor would be possible by employing NWs modified by multiple kinds of aptamers.

引用

页码：2211 / 2214

页数：4

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