An Idealized Child Throat that Mimics Average Pediatric Oropharyngeal Deposition

被引：42
作者：
Golshahi, L. [1 ]
Finlay, W. H. [1 ]
机构：
[1] Univ Alberta, Dept Mech Engn, Edmonton, AB T6G 2G8, Canada
来源：
AEROSOL SCIENCE AND TECHNOLOGY | 2012年 / 46卷 / 05期
基金：
加拿大自然科学与工程研究理事会;
关键词：
AEROSOL DEPOSITION; LUNG DEPOSITION; MOUTH; MODELS; SUITABILITY;
D O I：
10.1080/02786826.2012.667170
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
[No abstract available]
引用
收藏
页码：I / IV
页数：4
相关论文
共 21 条
[1]   Degree of throat deposition can explain the variability in lung deposition of inhaled drugs [J].
Borgstrom, Lars ;
Olsson, Bo ;
Thorsson, Lars .
JOURNAL OF AEROSOL MEDICINE-DEPOSITION CLEARANCE AND EFFECTS IN THE LUNG, 2006, 19 (04) :473-483
[2]   Aerosol drug delivery using heliox and nebulizer reservoirs: Results from an MRI-based pediatric model [J].
Corcoran, TE ;
Shortall, BP ;
Kim, IK ;
Meza, MP ;
Chigier, N .
JOURNAL OF AEROSOL MEDICINE-DEPOSITION CLEARANCE AND EFFECTS IN THE LUNG, 2003, 16 (03) :263-271
[3]   Predicting extrathoracic deposition from dry powder inhalers [J].
DeHaan, WH ;
Finlay, WH .
JOURNAL OF AEROSOL SCIENCE, 2004, 35 (03) :309-331
[4]   In Vitro Tests for Aerosol Deposition. I: Scaling a Physical Model of the Upper Airways to Predict Drug Deposition Variation in Normal Humans [J].
Delvadia, Renishkumar R. ;
Longest, P. Worth ;
Byron, Peter R. .
JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 2012, 25 (01) :32-40
[5]   Suitability of the upper airway models obtained from MRI studies in simulating drug lung deposition from inhalers [J].
Ehtezazi, T ;
Southern, KW ;
Allanson, D ;
Jenkinson, I ;
O'Callaghan, C .
PHARMACEUTICAL RESEARCH, 2005, 22 (01) :166-170
[6]   Recent advances in predictive understanding of respiratory tract deposition [J].
Finlay, Warren H. ;
Martin, Andrew R. .
JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 2008, 21 (02) :189-205
[7]   In vitro deposition measurement of inhaled micrometer-sized particles in extrathoracic airways of children and adolescents during nose breathing [J].
Golshahi, L. ;
Noga, M. L. ;
Thompson, R. B. ;
Finlay, W. H. .
JOURNAL OF AEROSOL SCIENCE, 2011, 42 (07) :474-488
[8]  
Golshahi L., 2011, J AEROSOL SCI UNPUB
[9]   In vitro intersubject and intrasubject deposition measurements in realistic mouth-throat geometries [J].
Grgic, B ;
Finlay, WH ;
Burnell, PKP ;
Heenan, AF .
JOURNAL OF AEROSOL SCIENCE, 2004, 35 (08) :1025-1040
[10]   Regional aerosol deposition and flow measurements in an idealized mouth and throat [J].
Grgic, B ;
Finlay, WH ;
Heenan, AF .
JOURNAL OF AEROSOL SCIENCE, 2004, 35 (01) :21-32
123