RhI-Catalyzed Benzo/[7+1] Cycloaddition of Cyclopropyl-Benzocyclobutenes and CO by Merging Thermal and Metal-Catalyzed C-C Bond Cleavages

被引：43
作者：
Fu, Xu-Fei [1 ]
Xiang, Yu [1 ]
Yu, Zhi-Xiang [1 ]
机构：
[1] Peking Univ, BNLMS, Key Lab Bioorgan Chem & Mol Engn, Coll Chem, Beijing 100871, Peoples R China
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2015年 / 21卷 / 11期
关键词：
benzo/[7+1; benzocyclobutene; carbonylation; eight-membered ring; rhodium; INTRAMOLECULAR 5+2 CYCLOADDITIONS; ELECTROCYCLIC REACTIONS; ENE-VINYLCYCLOPROPANES; RING-EXPANSION; ACTIVATION; INSERTION; ORIGINS; OLEFINS; ALKYNES; CARBOCYCLIZATION;
D O I：
10.1002/chem.201405712
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A Rh-catalyzed benzo/[7+1] cycloaddition of cyclopropyl-benzocyclobutenes (CP-BCBs) and CO to benzocyclooctenones has been developed. In this reaction, CPBCB acts as a benzo/7-C synthon and the reaction involves two C-C bond cleavages: a thermal electrocyclic ring-opening of the four-membered ring in CP-BCB and a Rh-catalyzed C-C cleavage of the cyclopropane ring.
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收藏
页码：4242 / 4246
页数：5
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