Adsorptive voltammetric determination of cisapride on carbon nanotubes paste electrode

The voltammetric behavior and electrochemical reaction mechanism of cisapride on carbon nanotubes paste electrode (CNTPE) has been investigated using cyclic and differential pulse voltammetry. In pH 6. 09 Britton-Robinson buffer, cisapride produced a sensitive oxidation peak at + 0. 89 V (vs. SCE). The oxidation of cisapride was an adsorption-controlled irreversible two-electron and one-proton process. The peak current varied linearly with the concentration of cisapride in the range from 4. 0 x 10 (-8) to 2. 0 x 10 (-5) mol/L. The detection limit was 1. 0 x 10(8) mol/L. The relative standard deviation (RSD) of ten measurements was 3. 68% for 2. 0 x 10 (-6) mol/L cisapride. The proposed method was employed in determining cisapride in cisapride tablets.