Rearrangement during halogenation of 2-hydroxy-1,2-diphenylpropan-1-one (α-methylbenzoin)

被引：7

作者：

Aitken, Kati M. ^{[1
]}

Aitken, R. Alan ^{[1
]}

机构：

[1] Univ St Andrews, EaStCHEM Sch Chem, St Andrews KY16 9ST, Fife, Scotland

来源：

TETRAHEDRON | 2008年 / 64卷 / 22期

关键词：

D O I：

10.1016/j.tet.2008.03.043

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of 2-hydroxy-1,2-diphenylpropan-1-one 1 with SOCl2 or PBr3 gives, respectively, the 3-chloro- and 3-bromo-1,2-diphenylpropan-1-ones 4 and 6. The expected 2-chloro- and 2-bromo-1,2-diphenylpropan-1-ones 2 and 5 can, however, be formed by treatment of 1,2-diphenylpropan-1-one 8 with Cl-2 or Br-2/AlCl3. The four halogenated products are characterised by H-1 and C-13 NMR spectroscopy for the first time. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：5217 / 5220

页数：4

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