Sensitive fluorescence detection of lysozyme using a tris(bipyridine)ruthenium(II) complex containing multiple cyclodextrins

被引:27
作者
Zhang, Fan [1 ]
Zhao, Ying-Ying [1 ]
Chen, Hong [1 ]
Wang, Xiu-Hua [1 ]
Chen, Qiong [1 ]
He, Pin-Gang [1 ]
机构
[1] E China Normal Univ, Dept Chem, Shanghai 200241, Peoples R China
关键词
HOST-GUEST RECOGNITION; BETA-CYCLODEXTRIN; ELECTROCHEMILUMINESCENCE APTASENSOR; METALLOCYCLODEXTRINS SYNTHESIS; ANALYTICAL-CHEMISTRY; INCLUSION COMPLEXES; MOLECULES; APTAMER; PROTEIN; ADAMANTANE;
D O I
10.1039/c5cc00428d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new series of photoactive metallocyclodextrins with increased fluorescence intensity upon binding with ssDNAs/aptamers has been demonstrated to sensitively and selectively detect lysozyme. The detection mechanism relies on the formation of an aptamer-lysozyme complex, which leads to reduction of fluorescence intensity.
引用
收藏
页码:6613 / 6616
页数:4
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