Phytochemical and GC-MS Analysis of Hydro Ethanolic Leaf Extract of Ocimum sanctum (L.)

被引:2
作者
Srivastava, Atul [1 ]
Subhashini [2 ]
Keshari, Anand Kumar [1 ]
Srivastava, Ragini [1 ]
机构
[1] Banaras Hindu Univ, Dept Biochem, Inst Med Sci, Varanasi 221005, Uttar Pradesh, India
[2] Banaras Hindu Univ, Dept Zool, MMV, Varanasi, Uttar Pradesh, India
来源
PHARMACOGNOSY RESEARCH | 2021年 / 13卷 / 04期
关键词
Phenolics; Flavonoids; Herbal drugs; Phytochemical; GC-MS analysis; ESSENTIAL OIL; PLANT;
D O I
10.5530/pres.13.4.16
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Background: The pharmacological efficiency of herbal drugs has shown to be effective as conventional pharmaceutical drugs. Preliminary screening of herbal extracts helps in analysing the bioactive compounds present. Ocimum sanctum, the queen of herbs keeps a spiritual importance in Indian culture and have important place in traditional medicinal system of India. Objectives: The present study was implement to investigate the preliminary phytochemical screening and GC-MS analysis of leaf extract of O. sanctum to determine the phyto-constituents. Materials and Methods: Leaves collected were dried, crushed and mixed with ethanol and water and further applied for extract preparation. The prepare extract was used for phytochemical and GC-MS analysis. Results: In qualitative phytochemical analysis tannins, carbohydrate, quinine, anthraquinones, coumarins, phlobatanins, alkaloids, flavonoids, glycosides, terpenoids, diterpenes, phenols were found present while GC-MS analysis showed Eugenol, Cyclohexane, bicyclo[7.2.0]undec-4-ene, 4,11,11-trimethyl-8-methylene, Oxatricyclo[8.2.0.0(4,6)]dodecane,,12-trimethyl-9-methylene, Tetracontane, Phytol were present in majority. Conclusion: The study concluded that O. sanctum leaf extracts contain many biological active compounds which could be exploited for a development of plant based drug.
引用
收藏
页码:233 / 237
页数:5
相关论文
共 21 条
[1]   Anthelmintic activity of essential oil of Ocimum sanctum and eugenol [J].
Asha, MK ;
Prashanth, D ;
Murali, B ;
Padmaja, R ;
Amit, A .
FITOTERAPIA, 2001, 72 (06) :669-670
[2]  
Babu N.R., 2018, J. Pharmacogn. Phytochem, V7, P1798
[3]  
BALANDRIN MF, 1993, ACS SYM SER, V534, P2
[4]   PEROXYL AND HYDROXYL RADICAL SCAVENGING ACTIVITY OF SOME NATURAL PHENOLIC ANTIOXIDANTS [J].
CHIMI, H ;
CILLARD, J ;
CILLARD, P ;
RAHMANI, M .
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1991, 68 (05) :307-312
[5]   GC-MS analysis of bioactive compounds from the whole plant ethanolic extract of Evolvulus alsinoides (L.) L [J].
Gomathi, Duraisamy ;
Kalaiselvi, Manokaran ;
Ravikumar, Ganesan ;
Devaki, Kanakasabapathi ;
Uma, Chandrasekar .
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 2015, 52 (02) :1212-1217
[6]   Antioxidant Activity of Eugenol: A Structure-Activity Relationship Study [J].
Gulcin, Ilhami .
JOURNAL OF MEDICINAL FOOD, 2011, 14 (09) :975-985
[7]  
Gupta, 1995, ADV HORTICULTURE, P627
[8]  
Heinrich M, 2000, PHYTOTHER RES, V14, P479, DOI 10.1002/1099-1573(200011)14:7<479::AID-PTR958>3.0.CO
[9]  
2-2
[10]  
Jan Shumaila, 2013, Osong Public Health Res Perspect, V4, P246, DOI 10.1016/j.phrp.2013.09.003