Different etiologies and prognoses of optic neuritis in demyelinating diseases

被引：48

作者：

Akaishi, Tetsuya ^{[1
]}

Nakashima, Ichiro ^{[1
]}

Takeshita, Takayuki ^{[2
]}

Kaneko, Kimihiko ^{[1
]}

Mugikura, Shunji ^{[3
]}

Sato, Douglas Kazutoshi ^{[1
]}

Takahashi, Toshiyuki ^{[1
,4
]}

Nakazawa, Toru ^{[2
]}

Aoki, Masashi ^{[1
]}

Fujihara, Kazuo ^{[1
,5
]}

机构：

[1] Tohoku Univ, Grad Sch Med, Dept Neurol, Sendai, Miyagi, Japan

[2] Tohoku Univ, Grad Sch Med, Dept Ophthalmol, Sendai, Miyagi, Japan

[3] Tohoku Univ, Grad Sch Med, Dept Diagnost Radiol, Sendai, Miyagi, Japan

[4] Yonezawa Natl Hosp, Dept Neurol, Yonezawa, Yamagata, Japan

[5] Fukushima Med Univ, Dept Multiple Sclerosis Therapeut, Fukushima, Japan

来源：

JOURNAL OF NEUROIMMUNOLOGY | 2016年 / 299卷

关键词：

Multiple sclerosis; Neuromyelitis optica spectrum disorder; Anti-MOG autoantibody; Optic neuritis; Optic MRI; Visual prognosis; NEUROMYELITIS-OPTICA; MULTIPLE-SCLEROSIS; VISUAL-ACUITY; MRI; ANTIBODY;

D O I：

10.1016/j.jneuroim.2016.09.007

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We compared the clinical features of optic neuritis (ON) that are frequently observed in various central nervous system demyelinating diseases, including multiple sclerosis (MS), anti-aquaporin 4 (AQP4) antibody- and anti-myelin oligodendrocyte glycoprotein (MOG) autoantibody-related diseases. Almost all the AQP4-ON patients were female, whereas half of the MOG-ON patients were male. The ON-onset age was younger in MS-ON and was older in AQP4-ON. The ON-lesion detected using optic MRI in the acute phase was longer in MOG-ON and showed severe swelling and twisting. The worst visual acuity was similar between the diseases; however, the final visual acuity was significantly worse in AQP4-ON. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：152 / 157

页数：6

共 14 条

[1] Lesion length of optic neuritis impacts visual prognosis in neuromyelitis optica [J].

Akaishi, Tetsuya ;

Nakashima, Ichiro ;

Takeshita, Takayuki ;

Mugikura, Shunji ;

Sato, Douglas Kazutoshi ;

Takahashi, Toshiyuki ;

Nishiyama, Shuhei ;

Kurosawa, Kazuhiro ;

Misu, Tatsuro ;

Nakazawa, Toru ;

Aoki, Masashi ;

Fujihara, Kazuo .

JOURNAL OF NEUROIMMUNOLOGY, 2016, 293 :28-33

[2] MRI and retinal abnormalities in isolated optic neuritis with myelin oligodendrocyte glycoprotein and aquaporin-4 antibodies: a comparative study [J].

Akaishi, Tetsuya ;

Sato, Douglas Kazutoshi ;

Nakashima, Ichiro ;

Takeshita, Takayuki ;

Takahashi, Toshiyuki ;

Doi, Hiroshi ;

Kurosawa, Kazuhiro ;

Kaneko, Kimihiko ;

Kuroda, Hiroshi ;

Nishiyama, Shuhei ;

Misu, Tatsuro ;

Nakazawa, Toru ;

Fujihara, Kazuo ;

Aoki, Masashi .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2016, 87 (04) :446-+

[3] Current Disease-Modifying Treatment of Multiple Sclerosis [J].

Derwenskus, Joy .

MOUNT SINAI JOURNAL OF MEDICINE, 2011, 78 (02) :161-175

[4] Comparison of Visual Acuity and Automated Perimetry Findings in Patients With Neuromyelitis Optica or Multiple Sclerosis After Single or Multiple Attacks of Optic Neuritis [J].

Fernandes, Danilo B. ;

Ramos, Renata de Iracema P. ;

Falcochio, Carolina ;

Apostolos-Pereira, Samira ;

Callegaro, Dagoberto ;

Ribeiro Monteiro, Mario Luiz .

JOURNAL OF NEURO-OPHTHALMOLOGY, 2012, 32 (02) :102-106

[5] The prognosis of idiopathic optic neuritis [J].

A. Ghezzi ;

V. Martinelli ;

M. Rodegher ;

M. Zaffaroni ;

G. Comi .

Neurological Sciences, 2000, 21 (Suppl 2) :S865-S869

[6]

Holladay JT, 1997, J REFRACT SURG, V13, P388

[7] Optic Neuritis, its Differential Diagnosis and Management [J].

Hoorbakht, Hedieh ;

Bagherkashi, Farid .

OPEN OPHTHALMOLOGY JOURNAL, 2012, 6 :65-72

[8] Treatment of neuromyelitis optica: Review and recommendations [J].

Kimbrough, Dorlan J. ;

Fujihara, Kazuo ;

Jacob, Anu ;

Lana-Peixoto, Marco A. ;

Leite, Maria Isabel ;

Levy, Michael ;

Marignier, Romain ;

Nakashima, Ichiro ;

Palace, Jacqueline ;

de Seze, Jerome ;

Stuve, Olaf ;

Tenembaum, Silvia N. ;

Traboulsee, Anthony ;

Waubant, Emmanuelle ;

Weinshenker, Brian G. ;

Wingerchuk, Dean M. .

MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2012, 1 (04) :180-187

[9] Contrast-enhanced MRI in acute optic neuritis: relationship to visual performance [J].

Kupersmith, MJ ;

Alban, T ;

Zeiffer, B ;

Lefton, D .

BRAIN, 2002, 125 :812-822

[10] Longitudinally extensive optic neuritis as an MRI biomarker distinguishes neuromyelitis optica from multiple sclerosis [J].

Mealy, Maureen A. ;

Whetstone, Anna ;

Orman, Gunes ;

Izbudak, Izlem ;

Calabresi, Peter A. ;

Levy, Michael .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 2015, 355 (1-2) :59-63

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