The role of miRNA125b in the progression of hepatocellular carcinoma

被引：9

作者：

Yang, Minghao ^{[1
]}

Wei, Sheng ^{[1
]}

Zhao, Huiyong ^{[1
]}

Zhou, Dachen ^{[1
]}

Cui, Xiao ^{[1
]}

机构：

[1] Anhui Med Univ, Hosp 2, Dept Gen Surg, 678 Furong Rd, Hefei, Peoples R China

来源：

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY | 2021年 / 45卷 / 05期

关键词：

miRNA125b; Hepatocellular carcinoma; Progression; PROGNOSTIC MARKER; MICRORNA-125B; MIR-125B; CELLS; PROLIFERATION; EXPRESSION; METASTASIS; SERUM; METHYLTRANSFERASE; RECURRENCE;

D O I：

10.1016/j.clinre.2021.101712

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Hepatocellular carcinoma (HCC) is one of the most common tumours worldwide, and identifying markers related to HCC is an important area of research. As a microRNA (miRNA), miRNA125b (miR-125b) plays an important role in the prediction and prognosis of HCC. In the past 10 years, with increasing research on miR-125b and HCC, the molecular mechanism of its relationship with the development of HCC has been elucidated. MiR-125b inhibits the development of HCC and is highly accurate in predicting HCC and is therefore a valuable predictive marker of HCC. This article summarizes the clinical application of miR-125b in HCC and the potential mechanism of its involvement in the progression of HCC. (c) 2021 Elsevier Masson SAS. All rights reserved.

引用

页数：7

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